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首页> 外文期刊>Journal of Medical Biochemistry >Lipoproteins and other Risk Factors for Cardiovascular Disease in a Student Population
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Lipoproteins and other Risk Factors for Cardiovascular Disease in a Student Population

机译：脂蛋白和其他学生心血管疾病的危险因素

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Summary Background: Cardiovascular disease (CVD) is a major cause of mortality and morbidity in many populations, especially in developed countries. The aim of the study was to analyze the lipid status in a student population at increased risk for CVD in comparison with students who are not at increased risk for CVD.Methods: This study included 238 students from the University of Novi Sad of both sexes (126 men and 112 women), with a mean age of 22.32±1.85 years. According to the body mass index (BMI) lower and higher than 25 kg/m2 and waist circumference (WC) of less and more than 94 cm (80 cm for females) the whole group of 238 students was divided into 2 subgroups: the group at increased risk for CVD (Group 1) and the group at lower risk for CVD (Group 2). Total cholesterol - TCH, triglycerides - TG, high density lipoprotein cholesterol - HDL-c, low density lipoprotein cholesterol - LDL-c, very low-density lipoprotein cholesterol - VLDL-c concentrations were determined and the index of atherosclerosis (IA), established risk factors RF-TCH/HDL-c ratio and non-HDL-c/HDL-c ratio were mathematically calculated.Results: The values of TCH, LDL-c, non-HDL-c, VLDL-c and TG were significantly higher in Group 1 compared to Group 2 (P<0.001). IA, non-HDL-c/HDL-c and RF-TCH/HDL-c ratio were also significantly higher (P<0.001), while HDL-c was significantly lower (p<0.01) in Group 1 compared to controls. These results were not influenced by gender in both groups of subjects.Conclusions: The data suggest that increased anthropometric parameters are followed by increased lipoprotein status in the group of students at increased risk for CVD and screening of the lipid status is necessary in students, especially in those who are at increased risk for CVD.
机译：发明背景：心血管疾病（CVD）是许多人群（尤其是在发达国家）死亡率和发病率的主要原因。这项研究的目的是分析与未患CVD风险增加的学生相比，患CVD风险增加的学生人群中的脂质状况。方法：本研究包括238名来自诺维萨德大学的男女学生（ 126名男性和112名女性），平均年龄为22.32±1.85岁。根据低于和高于25 kg / m2的体重指数（BMI）和小于和大于94 cm（女性为80 cm）的腰围（WC），将整个238名学生分为2个亚组：患心血管疾病的风险较高（第1组），而患心血管疾病的风险较低（第2组）。确定总胆固醇-TCH，甘油三酸酯-TG，高密度脂蛋白胆固醇-HDL-c，低密度脂蛋白胆固醇-LDL-c，极低密度脂蛋白胆固醇-VLDL-c的浓度并确定动脉粥样硬化（IA）的指数危险因素的RF-TCH / HDL-c比值和非HDL-c / HDL-c比值均通过数学计算得出。结果：TCH，LDL-c，非HDL-c，VLDL-c和TG值显着升高组1与组2相比（P <0.001）。与对照组相比，IA，IAL，非HDL-c / HDL-c和RF-TCH / HDL-c的比率也显着更高（P <0.001），而HDL-c显着更低（p <0.01）。结论：数据表明，在增加心血管疾病风险的学生组中，人体测量参数增加后脂蛋白状态增加，因此有必要筛查脂质状态，尤其是对学生而言在那些有增加CVD风险的人中。

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