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首页> 外文期刊>Journal of medical bacteriology. >Enteroaggregative Escherichia coli (EAEC): An Emerging Enteric Pathogen in South of Iran
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Enteroaggregative Escherichia coli (EAEC): An Emerging Enteric Pathogen in South of Iran

机译：肠聚合性大肠埃希菌（EAEC）：伊朗南部的新兴肠病原体

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Background: Enteroaggregative E. coli (EAEC) is increasingly recognized as a cause of often persistent diarrhea in children and adults in both developing and developed countries. The aim of the present study was to investigate the presence and the frequency of EAEC as etiologic agent of diarrhea in Shiraz.Methods: A total of 715 stool samples were collected from patients with diarrhea in Shiraz. Diarrheagenic E. coli were isolated by biochemical tests and culture from 715 stool samples collected from different hospitals. Diarrheagenic E. coli strains isolated from diarrheal stool samples were examined for the detection of the aggR gene by Real time PCR and PCR method.Results: In this study, a total of 101 (14.12%) diarrheagenic E. coli were isolated from 715 stool samples collected from different hospitals. The infected patients were 58 (57%) males and 43 (43%) females. Out of these 101 diarrheagenic E. coli identified, 5 were confirmed as EAEC inpatient. The EAEC strains were isolated from 3 of the 43 females (43%) and 2 of the 58 males ( 57%) with the mean age of 11.4±1.2 age. In this study, 5 EAEC strains were isolated from one patient with bloody diarrhea and 4 patients with watery diarrhea. The high prevalence of EAEC solates was also found in watery diarrhea.Conclusion: We therefore, recommend the routine isolation and identification of EAEC strains from patient with diarrhea in all the clinical laboratories and other pathotype diarrheagenic E.coli in Iran.
机译：背景：在发展中国家和发达国家，肠聚合性大肠杆菌（EAEC）日益被认为是儿童和成人经常腹泻的原因。本研究的目的是调查设拉子在腹泻的病因中EAEC的存在和频率。方法：从设拉子的腹泻患者中收集了715份粪便样本。通过生化测试和从不同医院收集的715份粪便样品中分离培养出腹泻性大肠杆菌。通过实时PCR和PCR方法检测了从腹泻粪便样本中分离出的腹泻性大肠杆菌菌株的aggR基因的检测结果。本研究共从715份粪便中分离出101种（14.12％）腹泻性大肠杆菌。从不同医院收集的样本。感染的患者为男性（58名，占57％）和女性43名（，占43％）。在确定的101例腹泻性大肠杆菌中，有5例被确认为EAEC住院患者。从43名女性中的3名（43％）和58名男性中的2名（57％）分离出EAEC菌株，平均年龄为11.4±1.2岁。在这项研究中，从一名血性腹泻患者和四名水性腹泻患者中分离出5株EAEC菌株。结论：我们因此建议在伊朗的所有临床实验室和其他致病型腹泻性大肠杆菌中，从腹泻患者中常规分离和鉴定EAEC菌株，并对其进行鉴定。

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