首页> 外文期刊>Journal of Ophthalmic Inflammation and Infection >Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography
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Macular retinal and choroidal thickness in unilateral relentless placoid chorioretinitis analyzed by swept-source optical coherence tomography

机译:扫描源光学相干断层扫描分析单侧持续性乳突脉络膜视网膜炎的黄斑部视网膜和脉络膜厚度

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The purpose of this study is to evaluate the retinal and choroidal thickness of the macular region in patients with unilateral relentless placoid chorioretinitis (RPC) and macular involvement. Patients diagnosed with RPC affecting only one eye underwent a comprehensive ophthalmologic examination including best-corrected visual acuity (BCVA), axial length (AL) measurement, slit-lamp examination, and color fundus and autofluorescence photography. The macular region was scanned by swept-source optical coherence tomography in the 1,050-nm wavelength. Automated segmentations of the retina and the choroid were used to obtain the corresponding thickness values. A total number of three patients (two men and one woman; age range 17 to 62 years) were included. Eyes with clinically evident RPC had a mean AL of 24.62 - 0.11 mm, whereas in the clinically healthy fellow eyes, the mean AL was 24.65 - 0.03 (p?=?0.70). The mean BCVA was 0.93 - 0.16 in eyes with RPC, and 1.0 in all the fellow eyes (p?=?0.70). Slit-lamp examination did not reveal any sign of vitreous inflammation in any cases. The mean macular retinal thickness was 288.10 - 10.22 ?m in eyes with RPC, and 300.30 - 7.17 ?m in the healthy fellow eyes (p?=?0.20). The mean central choroidal thickness was 260.70 - 140.60 ?m in eyes with RPC, and 262.30 - 123.10 ?m in the fellow eyes (p?=?0.99). The mean macular choroidal thickness was 248.60 - 128.40 and 255.10 - 123.60 ?m, respectively (p?=?0.99). The pathogenesis of RPC remains unknown. No changes in the retinal and choroidal thickness were observed in the macular area of eyes diagnosed with RPC with macular involvement compared with the asymptomatic healthy fellow eyes. Further prospective studies are warranted in order to investigate the role of the choroid in cases of RPC.
机译:这项研究的目的是评估单侧持续性乳突性脉络膜视网膜炎(RPC)和黄斑受累患者的黄斑区视网膜和脉络膜厚度。被诊断患有RPC且仅影响一只眼睛的患者接受了全面的眼科检查,包括最佳矫正视力(BCVA),轴向长度(AL)测量,裂隙灯检查以及彩色眼底和自发荧光照相。通过在1050nm波长下的扫频光学相干断层扫描术扫描黄斑区域。视网膜和脉络膜的自动分割用于获得相应的厚度值。总共包括三名患者(两名男性和一名女性;年龄范围为17至62岁)。具有临床上明显的RPC的眼睛的平均AL为24.62-0.11 mm,而在临床上健康的另一只眼睛中,平均AL为24.65-0.03(p?=?0.70)。 RPC眼的平均BCVA为0.93-0.16,所有其他眼的平均BCVA为1.0(p?=?0.70)。在任何情况下,裂隙灯检查均未发现任何玻璃体炎症迹象。黄斑视网膜平均厚度在RPC眼中为288.10-10.22μm,在健康人眼中为300.30-7.17μm(p = 0.20)。 RPC眼的平均中央脉络膜厚度为260.70-140.60μm,另一只眼的平均中央脉络膜厚度为262.30-123.10μm(p = 0.99)。黄斑脉络膜平均厚度分别为248.60-128.40和255.10-123.60?m(p?=?0.99)。 RPC的发病机制仍然未知。与无症状健康的同龄人眼睛相比,在诊断为RPC并伴有黄斑累及的眼睛的黄斑区域中未观察到视网膜和脉络膜厚度的变化。为了调查脉络膜在RPC病例中的作用,有必要进行进一步的前瞻性研究。

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