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首页> 外文期刊>Journal of Oral Microbiology >Investigation of the prevalence of Tn916/Tn916-like elements in oral streptococci
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Investigation of the prevalence of Tn916/Tn916-like elements in oral streptococci

机译：口腔链球菌中Tn916 / Tn916样元素的患病率调查

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Streptococcus species are the most abundant genera in the oral microbiota. The prevalence of antibiotic resistant oral streptococci is on the increase and the most reported antibiotic resistance profile in oral streptococci include, among several antibiotics, resistance to β-lactams antibiotics, macrolides and tetracycline. Several studies have shown that majority of the antibiotic resistance genes that have been isolated in oral streptococci are usually associated with mobile genetic elements such as plasmids and conjugative transposons. In the current study, we used molecular based techniques to screen a total of 100 clinical oral streptococci strains isolated in Norway for the presence of Tn916/Tn916-like elements. We also investigated the diversity of these elements in oral streptococci by Restriction Fragment Length Polymorphism (RFLP) and DNA sequencing. It was found that a total of 34 strains were positive for tetracycline resistance gene, tet(M), and integrase gene (int) belonging to the T...
机译：链球菌是口腔微生物群中最丰富的属。口服链球菌对抗生素的耐药性呈上升趋势，口服链球菌的抗生素耐药性报告最多，其中包括对几种β-内酰胺类抗生素，大环内酯类和四环素类药物的耐药性。几项研究表明，口腔链球菌中分离出的大多数抗生素抗性基因通常与诸如质粒和结合转座子之类的移动遗传元件有关。在当前的研究中，我们使用基于分子的技术来筛选在挪威分离的总共100株临床口腔链球菌菌株中是否存在Tn916 / Tn916样元素。我们还通过限制性片段长度多态性（RFLP）和DNA测序研究了口腔链球菌中这些元素的多样性。发现共有34个菌株的四环素抗性基因，tet（M）和整合酶基因（int）属于T ....

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