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首页> 外文期刊>Journal of Oral Microbiology >Age-related prevalence and characteristics of Aggregatibacter actinomycetemcomitans in periodontitis patients living in Sweden
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Age-related prevalence and characteristics of Aggregatibacter actinomycetemcomitans in periodontitis patients living in Sweden

机译：居住在瑞典的牙周炎患者中与年龄相关的流行性和放线杆菌总数的特征

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Background: The presence of Aggregatibacter actinomycetemcomitans in patients with periodontitis has been extensively studied for decades.Objective: To study the prevalence of A. actinomycetemcomitans in younger and older periodontitis patients and to genetically characterize isolates of this bacterium.Design: Data from microbiological analyses of 3459 subgingival plaque samples collected from 1445 patients, 337 ‘younger’ patients (≤35 yrs) and 1108 ‘older’ patients (35 yrs) during 15 years (2000–2014), has been summerized. Isolates of A. actinomycetemcomitans were serotyped, leukotoxin promoter typed (JP2 and non JP2) and arbitrarily primed PCR (AP-PCR) genotyped. The origin of the JP2 genotype detected in the study population was determined.Results: The prevalence of A. actinomycetemcomitans was higher among younger than older patients and samples from the younger patients contained higher proportions of the bacterium. Serotype b was more prevalent among younger patients and the majorty of thes...
机译：背景：牙周炎患者中存在放线杆菌聚集性细菌已有数十年的广泛研究目的：研究年轻和老年牙周炎患者中放线放线杆菌的流行情况，并对这种细菌的分离物进行遗传学特征设计：来自微生物分析的数据在15年（2000-2014年）期间，从1445例患者，337例“年轻”患者（≤35岁）和1108例“老年”患者（> 35岁）中收集了3459个龈下菌斑样品。对放线放线杆菌的分离株进行血清分型，白细胞毒素启动子分型（JP2和非JP2），并进行任意引物PCR（AP-PCR）基因分型。结果：确定了年轻人群中放线菌的患病率高于老年患者，并且来自年轻患者的样本中细菌的比例更高。血清型b在年轻患者和大多数患者中更为普遍。

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