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首页> 外文期刊>Journal of pharmaceutical care. >An Evidence Practice Gap in Antiemetic Prescription with Chemotherapy
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An Evidence Practice Gap in Antiemetic Prescription with Chemotherapy

机译：止吐处方与化学疗法的证据实践差距

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Background: Chemotherapy induced nausea and vomiting is an added distress to patients burdened by the illness. In an effort to tackle the emetogenic potential of the agents, guidelines have been proposed to maintain uniformity in prescription and improvement in patient tolerance; but their utility and practice is not consistent. The aim of this clinical audit was to assess the antiemetic.practice and investigate the adherence to antiemetic clinical practice guidelineMethods: We performed an audit of the antiemetic practices in our tertiary referral centre. A.questionnaire based interview was completed at the outpatient visit to tabulate the dataResults: 99 (81.8%) patients received chemotherapy of at least low emetogenic risk. 83 (84%) patients received prophylaxis which was appropriate in 65% based on the our centre’s antiemetic regimen. This was however inappropriate in 76% of patients based on the international practice.parametersConclusions: Guidelines are not uniformly representative of all populations and modifications toguidelines based on local data are required to ensure success of such policies. There exist evidence-.practice gaps in antiemetic policies
机译：背景：化学疗法引起的恶心和呕吐使患病的患者更加痛苦。为了解决这些药剂的致呕作用，已经提出了一些指导方针，以保持处方的统一性和改善患者的耐受性。但是它们的效用和实践并不一致。此临床审核的目的是评估止吐方法，并调查对止吐临床实践指南的遵守情况。方法：我们在第三级转诊中心对止吐实践进行了审核。在门诊就诊时完成了基于问卷的访谈，以将数据制成表格。结果：99名（81.8％）患者接受了至少具有较低致呕风险的化疗。根据我们中心的止吐方案，有83（84％）名患者接受了预防，其中65％的患者是适当的。然而，根据国际惯例，这在76％的患者中是不适当的。参数结论：指南并不能统一代表所有人群，因此需要对基于本地数据的指南进行修改以确保此类政策的成功。止吐政策中存在证据-实践差距

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