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Isolation and Characterization of Antibiotic LL-AC541

机译:抗生素LL-AC541的分离与表征

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A new basic, water-soluble antibiotic designated LL-AC541, produced by a strain of Streptomyces hygroscopicus (NRRL 3111), was isolated as a hydrochloride sa [α]D25, — 58°, melting point, 200 to 215 C (decomposition). It is structurally related to streptothricin but does not contain β-lysine. Isolation procedures, physicochemical properties, antimicrobial spectrum, and in vivo testing results are presented. Another very closely related antibiotic obtained from the same fermentation is briefly described.
机译:分离了由吸水链霉菌(NRRL 3111)菌株生产的一种新的碱性水溶性抗生素,命名为LL-AC541,为盐酸盐; [α] D25,-58°,熔点,200至215℃(分解)。它在结构上与链霉素有关,但不含β-赖氨酸。介绍了分离程序,理化性质,抗菌谱和体内测试结果。简要描述了从同一发酵中获得的另一种密切相关的抗生素。

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