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Secreted Factors from Bifidobacterium animalis subsp. lactis Inhibit NF-κB-Mediated Interleukin-8 Gene Expression in Caco-2 Cells

机译:动物双歧杆菌亚种的分泌因子。乳酸抑制Caco-2细胞中NF-κB介导的白介素8基因表达。

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The objective of the present study was to evaluate the anti-inflammatory effects of Bifidobacterium animalis subsp. lactis strain BB12 in stimulated Caco-2 cells and to characterize the factors responsible for these anti-inflammatory effects. Characterization and purification studies indicate that BB12's anti-inflammatory factors might include a 50-kDa proteinaceous compound that is stable under a variety of heat and pH conditions.
机译:本研究的目的是评估动物双歧杆菌亚种的抗炎作用。乳酸菌BB12刺激的Caco-2细胞中,并表征引起这些抗炎作用的因素。表征和纯化研究表明,BB12的抗炎因子可能包括在多种热和pH条件下稳定的50 kDa蛋白质化合物。

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