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Effect of Serum on the Yield of Lymphocytic Choriomeningitis Virus in Baby Hamster Kidney Cells

机译:血清对仓鼠肾脏细胞淋巴细胞绒毛膜脑膜炎病毒产量的影响

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The yields of the Armstrong and WE strains of lymphocytic choriomeningitis virus in baby hamster kidney (BHK) cells cultivated in either bovine, calf, fetal bovine, or horse serum were investigated. Lines of BHK cells were established in these sera. When the infected cell lines were observed by immunofluorescence, the per cent fluorescing cells for a given virus strain did not vary. However, for both strains, the extracellular virus yields per cell were significantly greater in the fetal bovine-cell line than in the other serum-cell lines.
机译:研究了在牛,小牛,胎牛或马血清中培养的仓鼠肾脏(BHK)细胞中的淋巴细胞绒毛膜脑膜炎病毒的Armstrong和WE菌株的产量。在这些血清中建立了BHK细胞系。当通过免疫荧光观察被感染的细胞系时,给定病毒株的荧光细胞百分数没有变化。但是,对于这两种菌株,胎牛细胞系中每个细胞的细胞外病毒产量均明显高于其他血清细胞系。

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