• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Infection and immunity >Biological activities of pyochelins: iron-chelating agents of Pseudomonas aeruginosa.
【24h】

Biological activities of pyochelins: iron-chelating agents of Pseudomonas aeruginosa.

机译：pyyochelins的生物活性：铜绿假单胞菌的铁螯合剂。

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Strains of Pseudomonas aeruginosa able to grow readily in serum (serum resistant) produce siderophores in large quantity, enabling them to extract iron from transferrins. The term pyochelin has been proposed for this group of compounds. Pyochelin extractable with ethyl acetate and designated pyochelin A appears to be a mixture of catechols and other phenolates. The structures of water-soluble siderophores, designated pyochelin B, have not been determined. Pyochelins enabled growth in serum of strains of serum-sensitive P. aeruginosa and other gram-negative bacilli. Serum-resistant strains of P. aeruginosa tended to be more virulent than equally toxigenic strains of the serum-sensitive group. However, incorporation of pyochelins into the inocula of serum-sensitive strains could reduce, rather than enhance, their virulence. Utilization of pyochelins by serum-sensitive strains of P. aeruginosa rendered some of these organisms resistant to pyocins which were otherwise lethal to them.
机译：能够在血清中轻易生长的铜绿假单胞菌菌株（抗血清）产生大量铁载体，使其能够从转铁蛋白中提取铁。对于这组化合物，已经提出了术语秋水仙素。可以用乙酸乙酯提取的泛素，命名为泛素A，似乎是儿茶酚和其他酚盐的混合物。尚未确定水溶性铁载体的结构，命名为PyochelinB。 pyyochelins使血清敏感铜绿假单胞菌和其他革兰氏阴性杆菌菌株的血清能够生长。铜绿假单胞菌的抗血清菌株比血清敏感组的同等产毒菌株倾向于更具毒性。但是，将pyochelins掺入血清敏感菌株的接种物中可降低而不是增强其毒力。铜绿假单胞菌的血清敏感性菌株利用了pyyochelins，使其中的某些生物对pyocins具有抗性，否则它们对它们具有致死性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号