Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis).

D M Williams; J Schachter; M H Weiner; B Grubbs

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Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis).

机译：宿主抗小鼠肺炎药（鼠衣原体沙眼衣原体）的抗体。

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In a murine model of chlamydial pneumonia employing murine Chlamydia trachomatis, immune serum given intranasally delayed death in nude (nuu) mice and prevented death in nu/+ mice. Serum-derived immunoglobulin G and A fractions and immune lavage fluid fractions containing immunoglobulins G and A were effective in producing protection when used to opsonize the murine C. trachomatis inoculum. In hyperclean mice (previously made germfree and then colonized with a limited flora nonpathogenic to mice) antibody given intravenously was ineffective. The effects of antibody and nonspecific stimulation of cell-mediated immunity (after previous infection with Histoplasma capsulatum) were additive in increasing host resistance to murine C. trachomatis.

机译：在使用鼠衣原体沙眼衣原体的鼠衣原体肺炎鼠模型中，鼻内给予免疫血清可延迟裸鼠（nu / nu）的死亡，并防止nu / +小鼠的死亡。当用于调理鼠源性沙眼衣原体接种物时，血清来源的免疫球蛋白G和A组分以及含有免疫球蛋白G和A的免疫灌洗液组分可以有效地产生保护作用。在高度清洁的小鼠中（先前已使其无菌，然后在对小鼠无致病性的有限菌群中定植），静脉内给予抗体无效。抗体和细胞介导的免疫的非特异性刺激（先前用荚膜组织胞浆菌感染后）的作用可增加宿主对沙眼衣原体的抵抗力。

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《Infection and immunity》 |1984年第3期|共5页
作者
D M Williams; J Schachter; M H Weiner; B Grubbs;
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中图分类医学免疫学;
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专利

1. Role of natural killer cells in infection with the mouse pneumonitis agent (murine Chlamydia trachomatis). [J] . D M Williams, J Schachter, B Grubbs Infection and immunity . 1987,第1期

机译：天然杀伤细胞在小鼠肺炎药（沙眼衣原体沙眼衣原体）感染中的作用。
2. Protection of Wild-Type and Severe Combined Immunodeficiency Mice against an Intranasal Challenge by Passive Immunization with Monoclonal Antibodies to the Chlamydia trachomatis Mouse Pneumonitis Major Outer Membrane Protein [J] . Sukumar Pal, Jose Bravo, Ellena M. Peterson, Infection and immunity . 2008,第12期

机译：通过对沙眼衣原体小鼠肺炎小鼠肺炎主要外膜蛋白的单克隆抗体的被动免疫被动保护野生型和严重的联合免疫缺陷小鼠。
3. Mice immunized with a chlamydial extract have no increase in early protective immunity despite increased inflammation following genital infection by the mouse pneumonitis agent of Chlamydia trachomatis. [J] . S J Blander, A J Amortegui Infection and immunity . 1994,第9期

机译：用衣原体提取物免疫的小鼠尽管沙眼衣原体的小鼠肺炎药引起生殖器感染后炎症增加，但早期保护性免疫没有增加。
4. Activation of antigen presenting cells and induction of mucosal antibodies by Chlamydia trachomatis outer membrane peptide encapsulated within PLA-PEG nanoparticles [C] . Saurabh Dixit, Murtada Taha, Shree R. Singh, Annual NSTI nanotechnology conference and expo;TechConnect world innovation conference expo . 2014

机译：包裹在PLA-PEG纳米颗粒内的沙眼衣原体外膜肽激活抗原呈递细胞并诱导粘膜抗体
5. Extrusion as a Mechanism of Host Immune Response Evasion in a Chlamydia trachomatis Murine Infection Model [D] . Key, Charlotte Elise. 2019

机译：挤出作为衣原体的宿主免疫应答逃避的机制曲囊鼠丘脑感染模型
6. Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis). [O] . D M Williams, J Schachter, M H Weiner, 1984

机译：宿主抗鼠肺炎药（鼠衣原体沙眼衣原体）的抗体。
7. Role of Proapoptotic BAX in Propagation of Chlamydia muridarum (the Mouse Pneumonitis Strain of Chlamydia trachomatis) and the Host Inflammatory Response [O] . Jean-Luc Perfettini, David M. Ojcius, Charles W. Andrews, 2003

机译：促凋亡Bax在Chlamydia Muridarum繁殖中的作用（衣原体肺组织肺瘤的小鼠肺炎菌株）和宿主炎症反应

Antibody in host defense against mouse pneumonitis agent (murine Chlamydia trachomatis).

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