首页> 外文期刊>Infection and immunity >Contribution of fimbrial operons to attachment to and invasion of epithelial cell lines by Salmonella typhimurium.
【24h】

Contribution of fimbrial operons to attachment to and invasion of epithelial cell lines by Salmonella typhimurium.

机译:纤维操纵子对鼠伤寒沙门氏菌附着和侵袭上皮细胞系的贡献。

获取原文
           

摘要

The role of the Salmonella typhimurium fimbrial operons, lpf, fim, and pef, in adhesion to and invasion of epithelial cell lines was investigated. An S. typhimurium lpfC mutant was unable to adhere to or to invade HEp-2 cells, while an S. typhimurium fim deletion mutant did not attach to or enter HeLa cells. These results suggest that adhesion is a prerequisite for invasion and that distinct fimbrial adhesins select different target cells for invasion by S. typhimurium.
机译:研究了鼠伤寒沙门氏菌纤维操纵子lpf,fim和pef在粘附和侵袭上皮细胞系中的作用。鼠伤寒沙门氏菌lpfC突变体无法粘附或侵袭HEp-2细胞,而鼠伤寒沙门氏菌fim缺失突变体不附着或进入HeLa细胞。这些结果表明粘附是侵袭的先决条件,并且不同的纤维粘附素选择鼠伤寒沙门氏菌侵袭的不同靶细胞。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号