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首页> 外文期刊>Emerging Infectious Diseases >Sporadic Cryptosporidiosis Case-Control Study with Genotyping
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Sporadic Cryptosporidiosis Case-Control Study with Genotyping

机译：基因分型的偶发性隐孢子虫病病例对照研究

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We report a case-control study of sporadic cryp-tosporidiosis with genotyping of isolates from case-patients. A postal questionnaire was completed by 427patients and 427 controls. We obtained genotyping data onisolates from 191 patients; 115 were Cryptosporidiumhominis, and 76 were C. parvum. When all cryptosporidio-sis cases were analyzed, three variables were stronglyassociated with illness: travel outside the United Kingdom,contact with another person with diarrhea, and touchingcattle. Eating ice cream and eating raw vegetables wereboth strongly negatively associated with illness. Helping achild <5 years of age to use the toilet and the number ofglasses of tap water drunk at home each day were alsoindependently positively associated with risk. Eating toma-toes was negatively associated. For C. hominis infections,the strongly significant risk factors were travel abroad andchanging diapers of children <5 years of age. For C.parvum, eating raw vegetables and eating tomatoes werestrongly negatively associated with illness; touching farmanimals was associated with illness
机译：我们报告了一个病例对照研究，该病例为散发性低温-孢子虫病与病例患者分离株的基因型。 427名患者和427名对照组完成了邮政问卷。我们从191名患者中获得了分离株的基因型数据。 115例是隐孢子虫，76例是小隐孢子虫。在分析所有隐孢子虫病病例后，三个变量与疾病密切相关：英国以外旅行，与腹泻的另一个人接触以及接触牛。吃冰淇淋和吃生蔬菜都与疾病密切相关。帮助每天<5岁的儿童上厕所和每天在家喝杯自来水的数量也与患病风险呈正相关。食堂趾负相关。对于人形衣原体感染，最显着的危险因素是出国旅行和更换5岁以下儿童的尿布。对于小隐孢子虫，吃生蔬菜和吃西红柿与疾病有很大的负相关。接触法线动物与疾病有关

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