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首页> 外文期刊>Journal of Clinical and Diagnostic Research >Effect of Cellular Mobile Phone Use and Cetrizine on Hand-Eye Coordination and Visual Acuity FC09-FC12
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Effect of Cellular Mobile Phone Use and Cetrizine on Hand-Eye Coordination and Visual Acuity FC09-FC12

机译：使用手机和西替利嗪对手眼协调和视力的影响FC09-FC12

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Introduction: Cellular mobile phones are a major cause of distraction especially while driving. The aggressive and inappropriate use of cellular mobile phones has increased the risk of accidents. Similar alerts are available in literature for certain substances and drugs (e.g. second generation anti H1 drug ?Cetirizine) which also derange psychomotor performance and parameters of alertness.Aim: This study measured variations in hand-eye coordination and visual acuity due to use of cellular mobile phone in comparison to that of commonly used antihistaminic drug viz., single dose Cetirizine 10 mg.Materials and Methods: It was a single blind, single dose, interventional study, 100 healthy human volunteers divided into two groups. Baseline readings of all volunteers were noted. Group-I (n=50) was Cetirizine group (10mg orally stat), Group ?II (n=50) Cellular mobile phone user group. Alertness was tested on hand? steadiness tester (Reaction Time Index = RTI) and on Flicker?fusion apparatus (visual acuity - Critical Flicker Fusion Frequency per second= CFFF/sec). Baseline readings of all volunteers were noted before intervention. Baseline was compared with readings at three hour post-intervention and was analysed by paired t-test. Inter-group comparison of parameters was also done and was analysed by unpaired t-test.Results: The baseline RTI (95.46±41.74, 85.11±39.05) and CFF low and high (40.07±9.970, 40.76±9.309 and 40.42±9.035, 40.48±9.863) respectively, in Cetirizine group and Mobile user group were comparable. The RTI increased significantly (116.4±51.46, 102.8±49.26) in both the groups after intervention. However, there is no significant change in CFF intensity from baseline in either group post-intervention.Conclusion: Concurrent use of mobile phone while performing tasks, showed significant impairment of hand?steadiness which was comparable to that produced by single dose Cetirizine 10 mg and this may be one of the factors contributing to their close association with road traffic accidents.
机译：简介：蜂窝电话是导致分心的主要原因，尤其是在开车时。蜂窝移动电话的激进和不当使用增加了发生事故的风险。某些物质和药物（例如第二代抗H1药物西替利嗪）在文献中也有类似的警报，它们也会改变精神运动性能和警报参数。目的：本研究测量了由于使用细胞而导致的手眼协调性和视敏度变化相对于常用抗组胺药，即单剂量西替利嗪10毫克。材料与方法：这是一项单盲，单剂量，干预性研究，将100名健康人类志愿者分为两组。记录所有志愿者的基线读数。 Ⅰ组（n = 50）为西替利嗪组（口服静注10mg），Ⅱ组（n = 50）为手机用户。警觉性已经过测试？稳定性测试仪（反应时间指数= RTI）和闪烁融合设备上（视敏度-每秒临界闪烁融合频率= CFFF /秒）。干预前记录所有志愿者的基线读数。将基线与干预后三小时的读数进行比较，并通过配对t检验进行分析。结果：基线RTI（95.46±41.74，85.11±39.05）和CFF低和高（40.07±9.970，40.76±9.309和40.42±9.035，西替利嗪组和移动用户组分别为40.48±9.863）。干预后两组的RTI均显着增加（116.4±51.46，102.8±49.26）。但是，干预后两组中的CFF强度与基线相比均无显着变化。结论：在执行任务时同时使用手机显示出明显的手部稳定性受损，这与单剂量西替利嗪10 mg和这可能是导致其与道路交通事故密切相关的因素之一。

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