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首页> 外文期刊>Cardiology research and practice >Women Hospitalized for Acute on Chronic Decompensated Systolic Heart Failure Receive Less Furosemide Compared to Men
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Women Hospitalized for Acute on Chronic Decompensated Systolic Heart Failure Receive Less Furosemide Compared to Men

机译：与男性相比，女性为慢性失代偿的收缩期心力衰竭接受慢性失代偿的收缩性心力衰竭而接受较少的呋塞米

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The cumulative incidence of systolic heart failure is similar in men and women. However, major prognostic differences exist between genders. We sought to measure gender differences in furosemide prescribing patterns for patients with preexisting heart failure with reduced ejection fraction (HFrEF) admitted with Stage C acute decompensation, regardless of the underlying cause. We conducted a single-center retrospective analysis of patients admitted between 2015 and 2018 for acute on chronic decompensated HFrEF. Primary outcomes were differences in initial furosemide dose, total dose over the first 24?hours of hospitalization, and total dose during the entire hospitalization between women and men. Secondary outcomes included acute kidney injury (AKI), intubation, noninvasive ventilation (NIV), and in-hospital 30-day and 1-year mortality. We studied 434 patients (31% female) with similar baseline characteristics. Females received significantly less furosemide compared to men for the initial dose, over the first 24?hours, and throughout their hospitalization. However, AKI was more prevalent in women versus men (p=0.008). Females admitted for acute on chronic decompensated HFrEF receive significantly less furosemide when compared to men, but developed more AKI prior to discharge.
机译：男性和女性的收缩性心力衰竭的累积发生率类似。然而，在性别之间存在主要的预后差异。我们试图衡量呋塞末患者的呋塞米德患者的性别差异，患有患有阶段C急性失代偿的射血分数（HFREF），无论潜在的原因如何。我们对2015年至2018年急性解偿HFREF的急性反对的患者进行了单中心回顾性分析。主要结果是初始呋塞米剂量的差异，总剂量在前24小时的时间，以及在妇女和男性的整个住院期间的总剂量。二次结果包括急性肾脏损伤（AKI），插管，非侵入性通风（NIV）和医院30天和1年死亡率。我们研究了434名患者（31％的女性），基线特征相似。与男性为初始剂量的男性相比，女性接受的女性显着减少了呋塞米，在前24小时，以及整个住院期间。然而，AKI在女性与男性中更普遍（P = 0.008）。与男性相比，慢性失代偿的HFREF急性失代偿的HFREF的女性在慢性下降，但在放电之前开发了更多AKI。

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