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首页> 外文期刊>Health Psychology Open >Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study
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Psychological intervention based on psychoneuroimmunology improves clinical evolution, quality of life, and immunity of children with leukemia: A preliminary study

机译：基于心理学的心理干预术改善了白血病儿童的临床演进，生活质量和免疫力：初步研究

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We conducted a non-randomized, open-label clinical trial to assess whether a psychoneuroimmunology-based intervention enhanced immunity in children with acute lymphoblastic leukemia undergoing chemotherapy. In total, 16 children (44% female) received psychoneuroimmunology-based intervention, whereas 12 (50% female) received health psychoeducation (controls). The primary outcome was immunity markers, being clinical conditions the secondary outcome. Psychoneuroimmunology-based intervention increased immune markers (CD8+ T, B, and natural killer cells, serum immunoglobulin A, and immunoglobulin M) and quality of life, whereas it shortens the duration of fever and use of antipyretics, antibiotics, analgesics, and respiratory therapy. Immunity markers correlated with clinical conditions. Thus, psychoneuroimmunology-based intervention could reduce hospital cost and increase patient well-being.
机译：我们进行了非随机开放式临床试验，以评估基于精神病毒免疫学的干预是否会增强急性淋巴细胞白血病的儿童免疫力。共有16名儿童（女性44％）接受了基于精神神经免疫学的干预，而12（女性50％）接受了健康心理教育（控制）。主要结果是免疫标志物，临床条件是次要结果。基于精神神经免疫杂志的干预增加免疫标记（CD8 + T，B和天然杀伤细胞，血清免疫球蛋白A和免疫球蛋白M）和生活质量，而它缩短了退化，抗生素，镇痛药和呼吸治疗的发烧和使用的持续时间。免疫标记与临床病症相关。因此，基于精神神经免疫学的干预可以减少医院成本并增加患者福祉。

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