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首页> 外文期刊>Journal of King Saud University >The effect of sour cherry consumption on blood pressure, IL-6, CRP, and TNF-α levels: A systematic review and meta-analysis of randomized controlled trials sour cherry consumption and blood pressure
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The effect of sour cherry consumption on blood pressure, IL-6, CRP, and TNF-α levels: A systematic review and meta-analysis of randomized controlled trials sour cherry consumption and blood pressure

机译：酸樱桃消耗对血压，IL-6，CRP和TNF-α水平的影响：随机对照试验的系统评价和荟萃分析酸樱桃消耗和血压

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ObjectivesCherries are rich in polyphenols and anthocyanins and are believed to possess strong anti-inflammatory activity and cardio-protective effects. This study aim was to summarize the overall effect of sour cherry consumption on blood pressure and biomarkers associated with the inflammation.MethodsMEDLINE/PubMed, Cochrane, and Scopus were searched to find relevant papers up to April 2019. There were no time and language restrictions. This systematic review and meta-analysis was performed in accordance with the Preferred Items for Reporting of Systematic Reviews and Meta-Analyses (PRISMA) guidelines.ResultsEleven studies with 275 participants were included in this meta-analysis. Mean dose of the sour cherry was 170?mL/day, whilst mean duration of interventions was six weeks. Combined the results using random-effects model showed significant reductions in diastolic blood pressure levels following sour cherry consumption (WMD: ?2.32?mmHg, 95% CI: ?4.45, ?0.19, I2?=?39%), but there were no significant changes in systolic blood pressure (WMD: ?2.64?mmHg, 95% CI: ?5.84, 0.56, I2?=?33%), IL-6 levels (WMD: 0.12?pg/mL, 95% CI: ?0.13, 0.36, I2?=?49%), hs-CRP (WMD: ?0.13?mg/mL, 95% CI: ?0.47, 0.22, I2?=?49%) or TNF-α (WMD: ?0.07?pg/mL, 95% CI: ?0.18, 0.05, I2?=?00%).ConclusionSour cherry supplementation results a decrease in diastolic blood pressure, but elicits no significant effect on systolic blood pressure, IL-6 levels, CRP levels and TNF-α.
机译：玻璃和花青素富含多酚和花青素，据信具有强烈的抗炎活性和心脏保护作用。本研究旨在总结酸樱桃消费对与炎症相关的血压和生物标志物的总体影响。检测到2019年4月的相关论文。没有时间和语言限制。该系统审查和荟萃分析根据报告系统评价和荟萃分析（PRISMA）指南进行了处理。在此元分析中包含275名参与者的研究。酸樱桃的平均剂量为170？ml /天，而平均干预持续时间为六周。结合使用随机效应模型的结果表明，酸樱桃消耗后舒张压水平的显着减少（WMD：？2.32？mmHg，95％Ci：？4.45，？0.19，I2？=？39％），但没有收缩压的显着变化（WMD：？2.64？mmHg，95％Ci：Δ5.84,0.56，I2？=？33％），IL-6水平（WMD：0.12？PG / ml，95％CI：？0.13 ，0.36，I2？=？49％），HS-CRP（WMD：？0.13？Mg / ml，95％CI：α0.47,0.22，I2？=？49％）或TNF-α（WMD：？0.07？0.07？ pg / ml，95％ci：Δ0.18,0.05，i2？=Δ00％）。结论，樱桃补充结果降低了舒张压，但引发对收缩压，IL-6水平，CRP水平没有显着影响。 TNF-α。

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