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首页> 外文期刊>Journal of Molecular Biology Research >Comparison of Magnesium Sulfate and Nifedipine in Prevention of Preterm Labor
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Comparison of Magnesium Sulfate and Nifedipine in Prevention of Preterm Labor

机译：硫酸镁和硝苯地平预防早产劳动力的比较

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Introduction: Fetal and neonatal complications are more common in premature than full term pregnancy. Treatment of preterm labor and postpone delivery increases neonatal survival and better quality of life and reduces health care costs for premature infants. This study aimed to compare the effects of Nifedipine and Magnesium sulfate in arresting preterm labor and to adverse the effects of these drugs. Materials and Methods: This randomized and clinical trial study was performed on 100 pregnant women who were hospitalized for preterm labor pain. The participants were pregnant women with the gestational age of 28 to 34 weeks and with a single pregnancy and symptoms of preterm were studied. They were randomly divided into two equal groups. After not suppressing the pain by fluid therapy, in the first group Magnesium sulfate infused injection (N=50) was performed, while in the second group, oral Nifedipine were given. The research uses SPSS software (version 20) statistical software issue 20 to analyze the result of tests with descriptive statistical methods including independent T test and chi square test. Results: Mean maternal age, gestational age, parity converted Magnesium sulfate and Nifedipine group had no significant difference in statistical analysis. Delivery was delayed more than 48 hours in 48% (24 person) of cases in the Magnesium sulfate group and in 72% (36 person) in Nifedipine group (p=0.03). A statistically significant difference in response to treatment was more in group of Nifedipine. Conclusion: The results showed that Nifedipine is more effective than Magnesium sulfate in postponing delivery (more than 48 hours), producing minimal side effect, having adequate price and applying an easy use method. Therefore, Nifedipine, as a tocolytic, can be a good substitute for Magnesium sulfate in preterm labor treatment.
机译：介绍：胎儿和新生儿并发症在早产比于全年怀孕时更常见。早产劳动和推迟递送的治疗增加了新生儿生存和更好的生活质量，并降低了早产儿的医疗费用。本研究旨在比较硝苯地平和硫酸镁在逮捕早产和对这些药物的影响的影响。材料和方法：该研究进行了100名孕妇，为早产患者住院治疗。参与者是孕妇的孕妇28至34周，并在单一的妊娠和早产的症状进行了研究。它们随机分为两个相等的群体。在不抑制通过流体疗法抑制疼痛后，在第一组中进行硫酸镁注入（N = 50），而在第二组中，给出口服硝苯地平。该研究使用SPSS软件（版本20）统计软件问题20分析测试结果，具有描述性统计方法，包括独立的T测试和CHI方检验。结果：平均孕产妇年龄，妊娠期，平均转化的硫酸镁和硝苯地平组在统计分析中没有显着差异。在硫酸镁基团中的48％（24人）中，在硫酸镁基团中的48％（24人）和硝苯胺基团中的72％（36人）中延迟了48小时（P = 0.03）。统计学上的对治疗响应的差异更大，更多的是硝苯地平。结论：结果表明，硝苯地平比硫酸镁在推迟递送（超过48小时）中更有效，产生最小的副作用，具有足够的价格和应用易用方法。因此，硝苯地平，作为毒性的，可以是早产劳动治疗中硫酸镁的良好替代品。

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