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Prenatal hepatitis B screening and associated factors in a high prevalence district of Lira, northern Uganda: a community based cross sectional study

机译:乌干达北部利拉普及地区产前乙型肝炎筛查及相关因素:基于社区的横断面研究

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Chronic hepatitis B Virus (HBV) infection affects 80-100 million people in sub-Saharan Africa and accounts for an estimated 650,000 deaths annually. The prevalence of active hepatitis B virus infection among women aged 15-64 in mid-Northern Uganda is about 5%. Lira district is among the high prevalence areas where government embarked on mass HBV screening since 2015 as a gateway for access to prevention, treatment services, and an effective response to the hepatitis?B epidemic. The current proportion of pregnant women screened and the factors associated with prenatal HBVscreening in Lira are not known despite the fact that women contribute largely to both vertical and horizontal transmission of HBV. This study aimed at determining the proportion of pregnant women screened for HBV and factors associated with prenatal HBV screening in Lira district. This was a community based cross sectional study conducted among 423 pregnant women in the sub counties of Aromo and Agweng in Lira district. Data were collected using open data kit and analysed using STATA version 14. The outcome variable was prenatal HBV screening while predictor variables were community, individual and health facility factors associated with HBV screening. Multivariable logistic regression was used to determine factors associated with prenatal HBV screening. Thirty five women (8.3%) had been screened for HBV during the current pregnancy. Factors associated with prenatal HBV screening in Lira included perceived risk (Adjusted Odds Ratio (AOR) 3.78, 95% CI 1.01-6.14), respondent's age (AOR?=?3.98, 95% CI 1.39-5.09), husband/partner's education (AOR?=?3.34, 95% CI 1.10-5.12) and past failure to access to HBV screening services at government health facilities (AOR?=?6.44, 95% CI 2.10-8.02). The level of HBV screening among pregnant women in Lira was low and is mainly associated with perceived risk, age, access to HBV screening services and spousal education level. More effort is needed in creating mass awareness on the need and importance of HBV screening most especially among pregnant women.
机译:慢性乙型肝炎病毒(HBV)感染在撒哈拉以南非洲影响80-100万人,每年估计650,000人死亡。乌干达中北部15-64岁的女性中活性乙型肝炎病毒感染的患病率约为5%。 Lira District是自2015年以来,政府在2015年开始筛选大众HBV筛选的高流行区域之一,作为进入预防,治疗服务和对肝炎的有效反应的门户。尽管女性在很大程度上促进了HBV的垂直和水平传播,但Lira在里拉筛选的目前患有孕妇的孕妇比例和与产前HBVScreening的因素尚不清楚。本研究旨在确定LIRA区产前HBV筛选HBV筛选的孕妇的比例和与产前HBV筛查相关的因素。这是一个基于社区的横断面分布研究,在里拉区Agweng的423名孕妇中进行。使用开放数据套件收集数据并使用STATA版本14进行分析。结果变量是产前HBV筛选,而预测因子变量是与HBV筛选相关的社区,个人和保健器件因素。多变量逻辑回归用于确定与产前HBV筛选相关的因素。在目前的怀孕期间,HBV筛查了三十五名女性(8.3%)。与LIRA的产前HBV筛查相关的因素包括感知风险(调整的赔率比(AOR)3.78,95%CI 1.01-6.14),受访者年龄(AOR?=?3.98,95%CI 1.39-5.09),丈夫/合作伙伴的教育( AOR?=?3.34,95%CI 1.10-5.12)及其在政府卫生设施(AOR?= 6.44,95%CI 2.10-8.02)中获取过去的筛选服务。 Lira孕妇的HBV筛查水平低,主要与感知风险,年龄,获得HBV筛选服务和配偶教育水平有关。需要更多的努力来创造对HBV筛查的需要和重要性尤其是孕妇的需求和重要性。

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