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首页> 外文期刊>Journal of Clinical and Diagnostic Research >A Study of the Clinico-epidemiological Profile of COVID-19 Patients Admitted in a Tertiary Care Hospital in India
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A Study of the Clinico-epidemiological Profile of COVID-19 Patients Admitted in a Tertiary Care Hospital in India

机译：Covid-19患者临床流行病学剖面性研究所在印度高等教育医院入院

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India is the second country with the highest Coronavirus Disease-2019 (COVID-19) case burden in the world.In India, Maharashtra state has the highest number of cases.Aim: To study the clinico-epidemiological profile of COVID-19 patients admitted in a COVID-19 designated tertiary care centre in Pune, Maharashtra, India.Materials and Methods: The authors retrospectively investigated epidemiological, demographic, clinical, laboratory, radiological and treatment data of 413 Real Time-Polymerase Chain Reaction (RT-PCR) confirmed COVID-19 patients from 14th April 2020 to 30th June 2020.The data was analysed using the Mann-Whitney U test for continuous variables with non-normal distribution.Also, the multivariate logistic regression was used for analysis.Results: Among the 413 laboratory confirmed COVID-19 patients, 249 (60.29 %) were males, majority {87 (21.07%)} of the patients belonged to the age group of 51-60 years.The most common co-morbid condition found was diabetes mellitus {102 (24.69%)}.The most common symptoms were fever {185 (44.79%)} and cough {146 (35.35%)} followed by breathlessness {134 (32.45%)}.History of close contact with a confirmed COVID-19 case was present in 205 (49.64%) patients.The mean time from the onset of symptoms to hospital admission was 3.75 (SD±2.64) days.There was a strong association between increasing age and the need for intensive care.Total 63 (80.77%) out of 78 patients above 60 years of age had abnormal Chest X-Ray (CXR) findings during hospitalisation.Furthermore, the maximum number of deaths i.e., 31 patients (58.49%, n=53) occurred in the age group of more than 60 years of age.Conclusion: The findings suggest that increased value of serum Lactate Dehydrogenase (LDH) and Urea can be used as predictors for mortality rate.Patients aged more than 60 years are more prone for severe disease with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pneumonia and this subset of patients requires urgent medical attention.
机译：印度是第二个国家，冠状病毒病 - 2019年（Covid-19）案例负担。印度，马哈拉施特州的案件数量最多。研究Covid-19患者的临床流行病学概况在浦那的Covid-19指定的三级护理中心，Maharashtra，India。材料和方法：作者回顾性研究了413个实时聚合酶链反应（RT-PCR）的413个实时聚合酶链反应（RT-PCR）的追溯研究Covid-19患者从2020年4月14日至6月30日至6月30日。使用曼诺 - 惠特u测试分析了具有非正态分布的连续变量的数据。多变量逻辑回归用于分析。结果：在413实验室中确认的Covid-19患者，249名（60.29％）是男性，大多数{87％（21.07％）}患者属于51-60岁的年龄组。发现的最常见的共同病态是糖尿病Mellitus {102（ 24。 69％）}。最常见的症状是发烧{185（44.79％）}，咳嗽{146（35.35％）}随后是呼吸困难{134（32.45％）}。与确认的Covid-19案例密切联系的历史在205例（49.64％）患者中存在。症状发作到医院入院的平均时间为3.75（SD±2.64）天。增加年龄与重症监护的需要之间的强劲关联.Total 63（80.77％）在78例60岁以上的患者中出现异常的胸部X射线（CXR）检查结果。繁殖，死亡人数，即31名患者（58.49％，n = 53），在60多个以上发生岁月的结论：调查结果表明，血清乳酸脱氢酶（LDH）和尿素的增加值可用作死亡率的预测因素。超过60岁的患者对严重急性呼吸综合征冠状病毒2的严重疾病更容易发生严重疾病（ SARS-COV-2）肺炎和这种患者的患者需要紧急医疗。

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