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首页> 外文期刊>Frontiers in Medicine >A Retrospective Analysis of the Clinical and Epidemiological Characteristics of COVID-19 Patients in Henan Provincial People's Hospital, Zhengzhou, China
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A Retrospective Analysis of the Clinical and Epidemiological Characteristics of COVID-19 Patients in Henan Provincial People's Hospital, Zhengzhou, China

机译：河南省人民医院Covid-19患者临床和流行病学特征的回顾性分析，郑州郑州

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Objective: This study evaluated the clinical and epidemiological characteristics of patients with confirmed coronavirus disease 2019 (COVID-19). Methods: This retrospective study evaluated 29 patients with confirmed COVID-19 infection admitted to Henan Provincial People's Hospital between January 27 and February 27, 2020, with follow-up until April 01, 2020. Results: The median age of the patients was 56 years. Nineteen (19/29; 65.5%) had underlying conditions including cardiovascular disease, digestive disease, or type 2 diabetes mellitus. Twenty-two (22/29; 76%) had close contact with acquaintances or family members who were confirmed or probable COVID-19 cases. Many patients had white blood cell counts with abnormal neutrophil and lymphocyte numbers, abnormal hemoglobin concentration, coagulation profiles, and blood biochemistry, and increased infection markers. Mottling and multiple ground-glass opacities were seen in X-ray images of 19 patients (19/29; 65.5%). Most patients (23/29; 79.8%) received supplemental oxygen therapy and antibiotics (23/29; 79.8%) in addition to traditional Chinese medicines (26/29; 89.7%). The most frequent presenting symptoms were fever, cough, and sputum production. One patient, an 86-years-old woman with more than one underlying disease, died during follow-up. Patients with severe disease were significantly older and more likely to have been transferred from other healthcare facilities than those with mild disease. Anemia, decreased activated partial thromboplastin time, calcium, and albumin, and increased D-dimer and interleukin-6 were more frequent in severe disease. Need of oxygen therapy, mechanical ventilation, intravascular immunoglobulin, and duration of antibiotic therapy were increased in those with severe disease. Conclusions: Significant differences in demographical and clinical characteristics were observed in patients with moderate and severe COVID-19.
机译：目的：本研究评估了冠心病患者2019年患者的临床和流行病学特征（Covid-19）。方法：该回顾性研究评估了29例确诊的Covid-19感染患者于2020年1月27日至2月27日至2月27日至2月27日入境，直到2020年4月1日至2月27日。结果：患者的中位数为56岁。 20nteen（19/29; 65.5％）潜在的条件，包括心血管疾病，消化系统疾病或2型糖尿病。二十二人（22/29; 76％）与确认或可能的Covid-19案件的熟人或家庭成员密切接触。许多患者有白细胞计数嗜中性粒细胞异常和淋巴细胞数，血红蛋白浓度异常，凝固谱和血液化学，以及增加的感染标记。在19名患者的X射线图像（19/29; 65.5％）中看到斑点和多种磨砂玻璃不透射率。大多数患者（23/29; 79.8％）除了中药（26/29; 89.7％）外，还收到补充氧治疗和抗生素（23/29; 79.8％）。最常见的呈现症状是发烧，咳嗽和痰产生。一名患者，一个86岁的女性，患有一个以上的潜在疾病，在随访期间死亡。严重疾病的患者显着老化，更有可能从其他医疗保健设施转移，而不是轻度疾病。贫血，活化的部分血栓形成时间，钙和白蛋白，并且在严重疾病中增加了D-二聚体和白细胞介素-6的增加。需要氧气治疗，机械通气，血管内免疫球蛋白和抗生素治疗的持续时间增加，严重疾病。结论：中度和严重Covid-19患者观察到人口统计和临床特征的显着差异。

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