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首页> 外文期刊>Frontiers in Public Health >Epidemiological and Clinical Characteristics of COVID-19: A Retrospective Multi-Center Study in Pakistan
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Epidemiological and Clinical Characteristics of COVID-19: A Retrospective Multi-Center Study in Pakistan

机译：Covid-19的流行病学和临床特征：巴基斯坦的回顾性多中心研究

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The emergence of a pathogen responsible for a mysterious respiratory disease was identified in China and later called a novel coronavirus. This disease was named COVID-19. The present study seeks to determine the epidemiological and clinical characteristics of COVID-19 in Pakistan. This report will exhibit a linkage between epidemiology and clinical aspects which in turn can be helpful to prevent the transmission of the virus in Pakistan. A retrospective, multiple center study was performed by collecting the data from patients' with their demographics, epidemiological status, history of co-morbid conditions, and clinical manifestations of the disease. The data was collected from 31 public-sector and 2 private hospitals across Pakistan by on-field healthcare workers. A Chi-square test was applied to assess the relationship between categorical data entries. A total of 194 medical records were examined. The median age of these patients was found to be 34 years. A total of 53.6% active cases were present including 41.2% males and 12.4% females till the end of the study. Adults accounted for most of the cases (94.3%) of COVID-19. Fever (86.60%), cough (85.05%), fatigue (36.60%), dyspnea (24.74%), and gastrointestinal discomfort (10.31%) were among the most frequently reported signs and symptoms by the patients. However, 4.12% of the total patient population remained asymptomatic. The median duration of hospital stay was found to be 14 (0–19) days. The earliest source of the spread of the virus may be linked to the foreigners traveling to Pakistan. Spread among men was more as compared to women. A few cases were found to be positive, due to the direct contact with pets or livestock. Hypertension (7.73%), diabetes (4.64%), cardiovascular conditions (2.58%) were the most common co-morbidities. The percentage mortality was 2.50% with the highest mortality among elders.
机译：在中国中发现了负责神秘呼吸系统疾病的病原体的出现，后来称为新的冠状病毒。这种疾病被命名为Covid-19。本研究旨在确定巴基斯坦Covid-19的流行病学和临床特征。本报告将在流行病学和临床方面之间表现出联系，这反过来可能有助于防止在巴基斯坦传播病毒。通过将患者的人口统计，流行病学状态，共同病态病史和疾病的临床表现收集来自患者的数据来进行回顾性的多中心研究。通过现场医疗保健工人从31个公共部门和2个私营医院收集的数据。应用了Chi-Square测试以评估分类数据条目之间的关系。审查了共有194条医疗记录。这些患者的中位数被发现为34岁。总共有53.6％的活性病例，包括41.2％的男性和12.4％的女性，直到研究结束。成年人占Covid-19大多数情况（94.3％）。发烧（86.60％），咳嗽（85.05％），疲劳（36.60％），呼吸困难（24.74％）和胃肠道不适（10.31％）是患者最常报告的症状和症状之一。然而，4.12％的总患者人口仍然无症状。医院住宿期间的中位数被发现为14（0-19）天。最早的病毒传播来源可能与前往巴基斯坦的外国人联系起来。与女性相比，男人之间的蔓延更多。由于与宠物或牲畜直接接触，发现一些案例是阳性的。高血压（7.73％），糖尿病（4.64％），心血管条件（2.58％）是​​最常见的共同状况。百分比死亡率为2.50％，老年人死亡率最高。

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