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首页> 外文期刊>Orthopaedic Journal of Sports Medicine >PATELLOFEMORAL JOINT CARTILAGE RESTORATION WITH PARTICULATED JUVENILE ALLOGRAFT IN PATIENTS UNDER 21 YEARS OLD: POSTOPERATIVE MRI ANALYSIS AND RETURN TO SPORT RATES
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PATELLOFEMORAL JOINT CARTILAGE RESTORATION WITH PARTICULATED JUVENILE ALLOGRAFT IN PATIENTS UNDER 21 YEARS OLD: POSTOPERATIVE MRI ANALYSIS AND RETURN TO SPORT RATES

机译：21岁以下患者微粒幼年同种异体移植的Patellofemoral联合软骨恢复：术后MRI分析并返回体育率

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Background: Patellofemoral joint cartilage defects are difficult to treat due to their unique thickness and topography. Numerous cartilage restoration techniques are available to surgeons treating articular cartilage defects. However, patellofemoral joint restoration historically produces worse outcomes than tibiofemoral joint restoration. One cell-based option is particulated juvenile allograft cartilage (PJAC), though literature regarding the efficacy of this treatment is sparse, especially in patients under the age of 21 years. Hypothesis/ Purpose: The aim of this study is to investigate postoperative outcomes of PJAC for patellofemoral chondral defects using MRI and return to sport rates in this active, high-demand patient population. Methods: Patients at an urban tertiary care musculoskeletal institution who underwent PJAC for patellofemoral joint cartilage restoration were identified through records review. Patients 21 years old or younger with minimum clinical follow-up of 1 year and postoperative MRI at a minimum of 6 months after surgery were included. Cartilage restoration was assessed by MRI using the International Cartilage Repair Society’s standardized system. Sport activity was collected from medical records. Results: Thirty-six knees in 34 patients with a mean age of 16.1 ± 3.1 years old (range 10—21 years old) were analyzed. Mean follow-up was 32.1 months. Defects were located on the patella in 25 knees, and trochlea in 11 knees (Figure 1). There were no bipolar lesions in the cohort. Mean defect size was 2.47 cm ~(2). Twenty-four knees (66.7%) were graded either ‘normal’ or ‘nearly normal’, and 28 knees (77.8%) had greater than 50% of the defect filled on follow-up imaging. Return to sport rates among patients who participated in a sport preoperatively was 100%. Conclusion: Restoration of patellofemoral chondral defects in young patients with particulated juvenile allograft can be performed with satisfactory short-term efficacy, excellent postoperative MRI appearance, and very high rates of return to sport.
机译：背景：由于其独特的厚度和地形，髌螨间缺陷难以治疗。众多软骨恢复技术可用于治疗关节软骨缺陷的外科医生。然而，Patellofemoral联合修复历史上的结果比胫脂术联合恢复更差。一种基于细胞的选择是颗粒状幼年异种移植软骨（PJAC），尽管关于这种治疗的功效的文献稀疏，特别是在21岁以下的患者中。假设/目的：本研究的目的是使用MRI调查PJAC的PJAC术后结果，并在这种活跃，高需求患者人口中返回运动率。方法：通过记录审查，确定了一名城市三级护理肌肉骨骼机构的患者，用于髌椎间型关节软骨恢复。患者21岁或以下的临床随访1年和术后MRI至少在手术后至少6个月。通过MRI使用国际软骨修复社会的标准系统评估软骨恢复。从病历中收集体育活动。结果：34名膝盖34名患者，平均年龄为16.1±3.1岁（范围为10-21岁）。平均随访32.1个月。缺陷位于25膝上的髌骨，11个膝盖（图1）。队列中没有双极病变。平均缺陷尺寸为2.47厘米〜（2）。二十四个膝盖（66.7％）分级为“正常”或“几乎正常”，28个膝盖（77.8％）占缺陷的50％，填补了后续成像。术语术前参加运动的患者返回运动率为100％。结论：术后颗粒幼年异种移植患者的髌果实骨质缺损恢复可与令人满意的短期疗效，优异的术后MRI外观，非常高的返回运动率进行。

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