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The Most Common Clinical Features of Kawasaki Disease Patients in King Abdulaziz Medical City

机译:川崎病患者在阿卜杜勒齐王医学城市患者最常见的临床特征

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Background Kawasaki disease (KD) is an acute idiopathic vasculitis affecting the small and medium-sized arteries especially coronary artery (CA). it occurs?in childhood mostly below five years of age. Objective This study aims to identify the most common clinical features among KD patients in King Abdulaziz Medical City in Jeddah, Saudi Arabia from 1/1/1982 to 31/12/2018. Methods A case series study?was conducted in all KD patients that were admitted to the King Abdulaziz Medical City from 1/1/1982 to 31/12/2018 except those who?were diagnosed in other hospitals or whose diagnosis has later changed. The identification of patient was done by using the International Classification of Diseases (ICD) coding for KD (ICD9 446.1).?Our data consisted of the patient’s file number, age?at presentation, gender, whether the patients received IVIG treatment or not,?number of days of fever before starting IVIG treatment, response to IVIG treatment, season in which the symptoms started and?clinical features based on body’s system. Result The study included 18 patients, 11?males showed that (55.6%) of patients met the criteria of typical KD and most of them were less than five years old. In addition, most patients were reported to have polymorphous rash, cough, irritability, vomiting, and a murmur. All patients who received intravenous immunoglobulin (IVIG) treatment?which demonstrated an improvement even though those who started the treatment after 10 days of fever. Conclusion In typical KD patients, the distribution of the clinical features was almost identical. However, there were some variations in them among atypical KD patients. Moreover, Evan though KD in our region is not common as in Japan, the incidence of giant aneurism was higher. In addition to that, this study and other study conducted in Saudi Arabia found that screened patients reported tachycardia more than patients in Japan. Recommendation As KD is still idiopathic, we recommend more details to be collected from the patients, especially consanguinity as it is common in Saudi Arabia.
机译:背景技术Kawasaki疾病(KD)是一种影响中小型动脉尤其是冠状动脉(CA)的急性特发性血管炎。它发生了?在童年之后大部分低于五岁。目的本研究旨在从1/1/1982年到2018年1月11日至12月31日,在沙特阿拉伯吉达吉德·阿布扎兹国王医学城KD患者中识别最常见的临床特征。方法案例课程研究?在所有KD患者中进行了从Abdulaziz国王1/1982年到2018年至12/2018中录取的所有KD患者进行,除了那些诊断在其他医院或后来改变的诊断。通过使用疾病(ICD)编码的国际分类(ICD9 446.1)进行患者的鉴定。 ?发烧前的天数,然后开始IVIG治疗,反应IVIG治疗,季节症状开始和基于身体系统的临床特征。结果研究包括18名患者,11例?男性表明,患者达到典型KD的标准,其中大多数人不到五岁。此外,据报道,大多数患者具有多态疹,咳嗽,烦躁,呕吐和杂音。所有接受静脉内免疫球蛋白(IVIG)治疗的患者?即使那些在发烧10天后开始治疗的人也表现出改善。结论在典型的KD患者中,临床特征的分布几乎相同。然而,在非典型KD患者中有一些变化。此外,Evan虽然在我们地区的KD虽然在日本不常见,但巨型动脉主义的发病率较高。除此之外,这项研究和其他在沙特阿拉伯进行的研究发现,筛查的患者报告了比日本患者的心动过速。 KD推荐仍然是发作性的,我们建议更多细节从患者中收集,特别是在沙特阿拉伯常见的血缘关系。

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