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REVIEW: Are Idiopathic and Chagasic Achalasia Two Different Diseases?

机译:评论:特发性和恰加尔性口疮是两种不同的疾病吗?

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摘要

Although Chagas' disease esophagopaty and idiopathic (primary) achalasia share several similarities, however, some differences between the two diseases have been noticed. To evaluate if treatment options and their results can be accepted universally, the authors review characteristics of both diseases in the international and Latin American literature. Neuronal denervation, sensitivity to gastrin, patient age, duration of symptoms, lower esophageal sphincter pressure, incidence of vigorous achalasia, and cancer risk are considered points of discrepancy between the maladies. Data with a high level of evidence base are scarce; however, differences between the diseases seem to exist, despite the fact that no influence on response to treatment was noticed.
机译:尽管恰加斯病的食管食道病和特发性(原发性)门失弛缓症有许多相似之处,但是,两种疾病之间仍存在一些差异。为了评估治疗方案及其结果是否可以被普遍接受,作者回顾了国际和拉丁美洲文献中两种疾病的特征。神经元神经支配,对胃泌素的敏感性,患者年龄,症状持续时间,食管括约肌压力降低,剧烈门失弛缓的发生率和癌症风险被认为是疾病之间的差异点。具有高水平证据基础的数据很少;然而,尽管没有发现对治疗反应的影响,但疾病之间似乎存在差异。

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