Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population

Balkrishan Sharma; Radhika Srinivasan; Yogesh Kumar Chawla; Shweta Kapil; Nitin Saini; Bhupesh Singla; Anuradha Chakraborthy; Naveen Kalra; Ajay Duseja; Radha Krishan Dhiman

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Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population

机译：维生素K缺乏引起的凝血酶原在印度人群肝细胞癌检测中的临床应用

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Background Alpha-fetoprotein (AFP) is a well known widely used biomarker for the detection of hepatocellular carcinoma (HCC); however, it suffers from a low sensitivity and specificity. Protein or prothrombin induced by vitamin K absence or antagonist II (PIVKA-II) is another tumor marker elevated in HCC but not extensively used.

机译：背景甲胎蛋白（AFP）是众所周知的用于检测肝细胞癌（HCC）的生物标志物；但是，其敏感性和特异性低。缺乏维生素K或拮抗剂II（PIVKA-II）诱导的蛋白质或凝血酶原是HCC中升高的另一种肿瘤标志物，但并未广泛使用。

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来源
《Hepatology International》 |2010年第3期|p.569-576|共8页
作者
Balkrishan Sharma; Radhika Srinivasan; Yogesh Kumar Chawla; Shweta Kapil; Nitin Saini; Bhupesh Singla; Anuradha Chakraborthy; Naveen Kalra; Ajay Duseja; Radha Krishan Dhiman;
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Protein induced by vitamin K absence or antagonist II; Alpha; fetoprotein; Hepatocellular carcinoma; Receiver operating characteristic curve; Area under curve;

机译：缺乏维生素K或拮抗剂II诱导的蛋白;甲胎蛋白肝细胞癌;接收机工作特性曲线;曲线下面积;

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1. Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population. [J] . Sharma B, Srinivasan R, Chawla YK, Hepatology international . 2010,第3期

机译：维生素K缺乏引起的凝血酶原在印度人群肝细胞癌检测中的临床应用。
2. Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population [J] . Balkrishan Sharma, Radhika Srinivasan, Yogesh Kumar Chawla, Hepatology international . 2010,第3期

机译：维生素K缺乏引起的凝血酶原在印度人群肝细胞癌检测中的临床应用
3. Role of serum prothrombin induced by vitamin K absence or antagonist-II in the early detection of hepatocellular carcinoma in patients with chronic hepatitis B virus infection [J] . YOUNG JOON YOON, KWANG-HYUB HAN, DO YOUNG KIM Scandinavian journal of gastroenterology. . 2009,第7期

机译：维生素K缺失或拮抗剂-II在慢性乙型肝炎病毒感染患者早期检测中血清凝血酶诱导的血清凝血酶蛋白的作用
4. Improved biomarker performance for the detection of hepatocellular carcinoma by inclusion of clinical parameters [C] . Wang Mengjun, Block Timothy M., Marrero Jorge, 2012 IEEE International Conference on Bioinformatics and Biomedicine. . 2012

机译：通过包括临床参数，改善了用于检测肝细胞癌的生物标志物性能
5. Transient increases in serum α fetoprotein and protein induced by vitamin K antagonist II levels following proton therapy does not necessarily indicate progression of hepatocellular carcinoma [D] . YOSHIDA MAIKO, 吉田舞子 2019

机译：质子治疗后血清α甲胎蛋白和维生素K拮抗剂II水平诱导的蛋白的短暂增加不一定表明肝细胞癌的进展
6. Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population [O] . Balkrishan Sharma, Radhika Srinivasan, Yogesh Kumar Chawla, 2010

机译：维生素K缺乏引起的凝血酶原在印度人群肝细胞癌检测中的临床应用
7. Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population [O] . Sharma, Balkrishan, Srinivasan, Radhika, Chawla, Yogesh Kumar, 2010

机译：维生素K缺乏引起的凝血酶原在印度人群肝细胞癌检测中的临床应用

Clinical utility of prothrombin induced by vitamin K absence in the detection of hepatocellular carcinoma in Indian population

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