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首页> 外文期刊>Magnetics, IEEE Transactions on >Magnetic Nanoparticles for Therapy and Diagnostics
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Magnetic Nanoparticles for Therapy and Diagnostics

机译：磁性纳米粒子的治疗和诊断

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摘要

The research and utilization of the magnetic nanoparticles in, e.g., biology and medicine have been preferentially oriented on magnetite ${rm Fe}_{3}{rm O}_{4}$ and maghemite $gamma-{rm Fe}_{2}{rm O}_{3}$. The complex oxides allow a better control of the magnetic properties in a desirable way. We demonstrate this approach on an example of the ${rm La}_{1-{rm x}}{rm Sr}_{rm x}{rm MnO}_{3}$ perovskites from the point of view of their use in self-controlled magnetic fluid hyperthermia and increase of contrast in magnetic resonance imaging. With materials possessing suitable values of transition temperature $T_{rm C}$, coercivity and magnetization, the heating power generated by the nanoparticles was estimated by two independent methods and they were finally employed in vitro and in vivo hyperthermia experiments.
机译：磁性纳米颗粒在例如生物学和医学领域的研究和利用已优先考虑磁铁矿<分子式> =“ inline”> $ {rm Fe} _ {3} {rm O} _ {4} $ 和磁赤铁矿 $ gamma- {rm Fe} _ {2} {rm O} _ {3} $ 。复合氧化物允许以期望的方式更好地控制磁性能。我们以 $ {rm La} _ {1- {rm x}} {rm Sr} _ {rm x} {rm MnO} _ {{3} $ 钙钛矿从其在自控磁流体热疗中的使用以及磁共振成像中对比度增加的角度出发。对于具有合适的转变温度值的材料 $ T_ {rm C} $ ，矫顽力和磁化强度，由通过两种独立的方法估算了纳米颗粒，最后将它们用于体外和体内热疗实验。

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