The Role of Melatonin in Rheumatic Diseases

B. Kalpakcioglu K. Senel

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The Role of Melatonin in Rheumatic Diseases

机译：褪黑激素在风湿性疾病中的作用

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Melatonin is a neurohormone that has attracted a great deal of attention, being frequently investigated in recent years. Due to its wide-spectrum of properties, melatonin has been suggested to be effective with respect to the etiology and treatment of several diseases. Its action on the immune system and antioxidant features has brought interest to this hormone's role in chronic inflammatory diseases. Furthermore, the detection of a correlation between the circadian release of melatonin and the rhythmic symptoms and signs of rheumatoid patients has led scientists to address its involvement in rheumatic diseases. Studies with suitable methodologies and broad perspectives are required in order to determine the functions of this neurohormone, whose effects are dependent on its physiological and pharmacological doses.

机译：褪黑素是一种引起广泛关注的神经激素，近年来受到了广泛的研究。由于其广泛的特性，褪黑激素已被认为在多种疾病的病因学和治疗方面是有效的。它对免疫系统和抗氧化功能的作用引起了人们对该激素在慢性炎症性疾病中的作用的兴趣。此外，检测到昼夜节律性褪黑激素释放与类风湿患者的节律性症状和体征之间的相关性，促使科学家解决了其与风湿性疾病有关的问题。为了确定这种神经激素的功能，需要进行适当的方法学和广泛的研究，神经激素的作用取决于其生理和药理剂量。

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《Infectious Disorders - Drug Targets》 |2009年第4期|p.453-456|共4页
作者
B. Kalpakcioglu K. Senel;
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作者单位

Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey.;

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正文语种 eng
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关键词
Melatonin, rhematoid arthritis, fibromyalgia, antioxidant, circadian rhythm;

机译：褪黑激素;类风湿关节炎;纤维肌痛;抗氧化剂;昼夜节律;

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1. The Role of Melatonin in Rheumatic Diseases [J] . B. Kalpakcioglu, K. Senel Infectious disorders drug targets . 2009,第4期

机译：褪黑激素在风湿性疾病中的作用
2. A Short History of the Gout and the Rheumatic Diseases. By W. S. C. Copeman, O.B.E., M.D., F.R.C.P., Senior Physician for Rheumatic Diseases, Middlesex Hospital; Chairman, British Empire Council on Rheumatic Diseases; President, European League Against Rheumatism; Chairman of the Faculty of the History of Medicine of the Worshipful Society of Apothecaries. 8? x 5? in. Pp. xii+236, with 19 figures. Select Bibliography. Index. 1964. Berkeley and Los Angeles, California: University of California Press. London: Cambridge University Press. Price 48s [J] . H. Jackson Burrows The Journal of Bone and Joint Surgery. British VolumecBritish Orthopaedic Association , Australian Orthopaedic Association , Canadian Orthopaedic Association . . . [et al] . 1965,第3期

机译：痛风和风湿病简史。米德尔塞克斯医院风湿病高级医师W.S.C. Copeman，O.B.E.，M.D.，F.R.C.P.大英帝国风湿病委员会主席;欧洲抗风湿病联盟主席;药剂师敬拜学会医学史系主任。 8？ x 5？ in。Pp。 xii + 236，有19个数字。选择书目。指数。 1964年。伯克利和加利福尼亚州洛杉矶：加利福尼亚大学出版社。伦敦：剑桥大学出版社。价钱48s
3. TEXTBOOK OF THE RHEUMATIC DISEASES. Edited by W. S. C. Copeman, O.B.E., M.D., F.R.C.P., Senior Physician, Arthur Stanley Institute for Rheumatic Diseases, Middlesex Hospital, Physician in charge of Department of Rheumatic Diseases, West London Hospital, Chairman, Empire Rheumatism Council, and late President, European League against Rheumatism; with twenty-five other contributors. Second edition. 9? x 7? in. Pp. viii+754, with 349 figures, 11 in colour. Index. 1955. Edinburgh and London: E. & S. Livingstone Ltd. Price 52s. 6d [J] . Norman Capener The Journal of Bone and Joint Surgery. British VolumecBritish Orthopaedic Association , Australian Orthopaedic Association , Canadian Orthopaedic Association . . . [et al] . 1955,第2期

机译：风湿病的教科书。由WSC Copeman，OBE，MD，FRCP，亚瑟·史丹利风湿病研究所高级医师，米德尔塞克斯医院，西伦敦医院风湿病科医师，帝国风湿病委员会主席，欧洲联盟反对联盟已故主席编辑风湿病;与其他25个贡献者。第二版。 9？ x 7？ in。Pp。 viii + 754，具有349个数字，11个颜色。指数。 1955年。爱丁堡和伦敦：E。＆S. Livingstone Ltd.价格52s。 6天
4. Amyloid, Cholinesterase, Melatonin, and Metals and Their Roles in Aging and Neurodegenerative Diseases [C] . DEBOMOY K. LAHIRI, DE-MAO CHEN, PREETI LAHIRI, International Conference on Natural Products and Molecular Medicine . 2005

机译：淀粉样蛋白，胆碱酯酶，褪黑激素和金属及其在衰老和神经退行性疾病中的作用
5. The role of MT1/MTt2 melatonin membrane receptors in mediating the neuroprotective effects of melatonin in Alzheimer's disease. [D] . O'Neal-Moffitt, Gina Ann. 2014

机译：MT1 / MTt2褪黑素膜受体在介导褪黑素在阿尔茨海默氏病中的神经保护作用中的作用。
6. The role of social determinants of health in the risk and prevention of group A streptococcal infection acute rheumatic fever and rheumatic heart disease: A systematic review [O] . Pasqualina M. Coffey, Anna P. Ralph, Vicki L. Krause 2018

机译：健康的社会决定因素在甲组链球菌感染急性风湿热和风湿性心脏病的风险和预防中的作用：系统综述
7. SP0110 Autoantibody standardisation in rheumatic diseases. the role of the european consensus finding study group on autoantibodies in rheumatic diseases (ECFSG) [O] . J. Rönnelid 2018

机译：SP0110在风湿病中的自身抗体标准化。欧洲共识发现研究组对风湿病患者自身抗体的作用（ECFSG）

The Role of Melatonin in Rheumatic Diseases

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