首页> 外文期刊>Journal of Cancer Research and Clinical Oncology >High-dose chronomodulated infusion of 5-fluorouracil (5-FU) and folinic acid (FA) (FF5–16) in advanced colorectal cancer patients
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High-dose chronomodulated infusion of 5-fluorouracil (5-FU) and folinic acid (FA) (FF5–16) in advanced colorectal cancer patients

机译:大剂量定时输注5-氟尿嘧啶(5-FU)和亚叶酸(FA)(FF5-16 )在结直肠癌患者中的应用

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摘要

. The best way to deliver infusional 5-fluorouracil (5-FU) and folinic acid (FA) has yet to be determined. The aim of this prospective phase II trial was to verify the tolerability, activity and efficacy of chronomodulated 5-FU-FA (FF5–16) every 3 weeks in 48 untreated patients (group A), and 28 pretreated and four non-measurable, advanced colorectal cancer (ACC) patients (group B).
机译:。输注5-氟尿嘧啶(5-FU)和亚叶酸(FA)的最佳方法尚待确定。这项前瞻性II期试验的目的是验证48例未经治疗的患者(A组)中每3周一次同步化5-FU-FA(FF5-16 )的耐受性,活性和功效不可衡量的晚期大肠癌(ACC)患者(B组)。

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