Enzyme shifts shape to edit DNA

首页> 外文期刊>Nature >Enzyme shifts shape to edit DNA

【24h】

Enzyme shifts shape to edit DNA

机译：酶改变形状以编辑DNA

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Structural biologists show how the DNA-cutting enzyme at the heart of a powerful gene-editing system changes shape to slice through DNA. Martin Jinek at the University of Zurich, Switzerland, and his colleagues studied the CRISPR-Cas system, in which an RNA molecule is used to guide and program the Cas enzyme to break through a specific segment of DNA.

机译：结构生物学家们展示了强大的基因编辑系统核心的DNA切割酶如何改变形状以切割DNA。瑞士苏黎世大学的Martin Jinek及其同事研究了CRISPR-Cas系统，该系统使用RNA分子来引导和编程Cas酶以突破特定的DNA片段。

著录项

来源
《Nature》 |2014年第7487期|134-134|共1页
作者

展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Spectroscopic characterization of a DNA-binding domain, Z alpha from the editing enzyme, dsRNA adenosine deaminase: Evidence for left-handed Z-DNA in the Z alpha-DNA complex [J] . Berger I., Manoharan R., Schwartz T., Biochemistry . 1998,第38期

机译：DNA结合结构域，编辑酶dsRNA腺苷脱氨酶的Z alpha的光谱表征：Z alpha-DNA复合物中左手Z-DNA的证据
2. Spectroscopic characterization of a DNA-binding domain, Z alpha from the editing enzyme, dsRNA adenosine deaminase: Evidence for left-handed Z-DNA in the Z alpha-DNA complex [J] . Berger I., Manoharan R., Schwartz T., Biochemistry . 1998,第38期

机译：DNA结合结构域，编辑酶dsRNA腺苷脱氨酶的Z alpha的光谱表征：Z alpha-DNA复合物中左手Z-DNA的证据
3. A Functional Variant in Ubiquitin Conjugating Enzyme E2 L3 Contributes to Hepatitis B Virus Infection and Maintains Covalently Closed Circular DNA Stability by Inducing Degradation of Apolipoprotein B mRNA Editing Enzyme Catalytic Subunit 3A [J] . Zhou Li, Ren Ji‐Hua, Cheng Sheng‐Tao, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2019,第5期

机译：泛素缀合酶E2 L3中的功能变体有助于乙型肝炎病毒感染，并通过诱导载脂蛋白B mRNA编辑酶催化亚基3a的降解保持共价闭合的圆形DNA稳定性
4. DNA Logic Circuits with a DNA Polymerase and a Nicking Enzyme [C] . Ryo Hirose, Satoshi Kobayashi, Ken Komiya International conference on parallel and distributed processing techniques and applications;PDPTA 2011 . 2012

机译：具有DNA聚合酶和切刻酶的DNA逻辑电路
5. Biochemical and structural studies of RNA and DNA editing enzymes [D] . Elias, Youssef 2007

机译：RNA和DNA编辑酶的生化和结构研究
6. A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift [O] . Hideki Terajima, Hikari Yoshitane, Tomoko Yoshikawa, -1

机译：A-to-I RNA编辑酶ADAR2调节光诱导的昼夜节律相移
7. DNA‐editing enzymes as potential treatments for heteroplasmic mtDNA diseases [O] . U. Zekonyte, S. R. Bacman, C. T. Moraes 2020

机译：DNA编辑酶作为异质MTDNA疾病的潜在治疗
8. Enzymes in Tuberculous Lesions Hydrolyzing Protein, Hyaluronic Acid and Chondroitin Sulfate: A Study of Isolated Macrophages and Developing and Healing Rabbit BCG Lesions with Substrate Film Techniques; the Shift of Enzyme pH Optima Towards Neutrality in [R] . Tsuda, T., Dannenberg, A. M., Ando, M., 1974

机译：在结核病灶水解蛋白分解酵素，透明质酸和硫酸软骨素：隔离巨噬细胞和发展和愈合兔BCG病变与基材膜技术的研究;酶最优pH值向中性转变

Enzyme shifts shape to edit DNA

摘要

著录项

相似文献

相关主题

期刊订阅