An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae

Wolfgang J. Philipp; Sylvie Poulet; Karin Eiglmeier

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An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae

机译：结核杆菌，结核分枝杆菌H37Rv的基因组图谱，以及与麻风分枝杆菌的比较

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摘要

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis, was constructed by using a twin-pronged approach. Pulsed-field gel electro- phoretic analysis enabled cleavage sites for Asn I and Dra I to be positioned on the 4.4-Mb circular chromosome, while, in parallel, clones from two cosmid libraries were ordered into contigs by means of fingerprinting and hybridization mapping.

机译：通过使用双管方法构建了结核杆菌结核分枝杆菌基因组的完整图谱。脉冲场凝胶电泳分析使Asn I和Dra I的切割位点位于4.4 Mb环状染色体上，同时，通过指纹图谱和杂交作图，将来自两个粘粒文库的克隆平行排列到重叠群中。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3132-3137|共6页
作者
Wolfgang J. Philipp; Sylvie Poulet; Karin Eiglmeier;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Comparison of the Construction of Unmarked Deletion Mutations in Mycobacterium smegmatis, Mycobacterium bovis Bacillus Calmette-Guérin, and Mycobacterium tuberculosis H37Rv by Allelic Exchange [J] . Martin S. Pavelka, William R. Jacobs Journal of bacteriology . 1999,第16期

机译：等位基因交换在耻垢分枝杆菌，牛分枝杆菌芽孢杆菌-Guérin和结核分枝杆菌H37Rv中未标记缺失突变的构建比较
2. Physical mapping of Mycobacterium bovis BCG Pasteur reveals differences from the genome map of Mycobacterium tuberculosis H37Rv and from M. bovis [J] . Wolfgang J. Philipp, Shamila Nair, Gérard Guglielmi, Microbiology . 1996,第11期

机译：分枝杆菌BOVI BCG Pasteur的物理映射揭示了与结核分枝杆菌H37RV和M.Bovis的基因组图谱的差异
3. The draft genome of Mycobacterium aurum, a potential model organism for investigating drugs against Mycobacterium tuberculosis and Mycobacterium leprae [J] . Jody Phelan, Arundhati Maitra, Ruth McNerney, International Journal of Mycobacteriology . 2015,第3期

机译：金黄色分枝杆菌的基因组草案，一种潜在的模型生物，可用于研究抗结核分枝杆菌和麻风分枝杆菌的药物
4. SIGNIFICANCE OF HEAVY FECAL SHEDDING OF MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS (MAP): COMPARISON OF FECAL CULTURE, REAL-TIME AND NESTED PCR TESTING [C] . Gilles R. G. Monif, Tsang L. Lin, J. Elliot Williams, Annual Meeting of the United States Animal Health Association . 2011

机译：重症粪便分枝杆菌的重要性植分数亚种分枝杆菌（MAP）：粪便培养，实时和嵌套PCR测试的比较
5. Comparative analyses of transport proteins encoded within the genomes of Mycobacterium tuberculosis and Mycobacterium leprae. [D] . Youm, Ji-Won. 2008

机译：结核分枝杆菌和麻风分枝杆菌基因组内编码的转运蛋白的比较分析。
6. An integrated map of the genome of the tubercle bacillus Mycobacterium tuberculosis H37Rv and comparison with Mycobacterium leprae. [O] . W J Philipp, S Poulet, K Eiglmeier, 1996

机译：结核杆菌结核分枝杆菌H37Rv的基因组图谱并与麻风分枝杆菌进行了比较。
7. An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae. [O] . Philipp, W J, Poulet, S, Eiglmeier, K, 1996

机译：结核杆菌，结核分枝杆菌H37Rv的基因组图谱，并与麻风分枝杆菌进行了比较。

An integrated map of the genome of the tubercle bacillus, Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae

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