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首页> 外文期刊>The Science of the Total Environment >The association between cooking oil fume exposure during pregnancy and birth weight: A prospective mother-child cohort study
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The association between cooking oil fume exposure during pregnancy and birth weight: A prospective mother-child cohort study

机译：孕妇食用油烟暴露与出生体重之间的关系：一项前瞻性母婴队列研究

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摘要

Effects of indoor air pollution on neonatal birth weight has been studied for many years. In China, cooking oil fumes are important parts of indoor air pollution. However, whether cooking oil fume exposure during pregnancy affects birth weight in China remains poorly understood. The objective of this study was to examine the association between pregnancy exposure to cooking oil fumes and birth weight in a newly established prospective mother-child cohort in China. We finally included 1420 pregnant women from 2013 to 2015 and follow up for one year until the offspring was born. According to self-reported exposure status, we categorized mothers into non-exposure group and exposed group or three exposure time subgroups, including 0 h/day, 0-1 h/day and >1 h/day respectively. By using multinomial logistics regression models, we found that pregnancy exposure to cooking oil fumes significantly increased the risk of large for gestational age (LGA, OR = 1.58,95% a = 1.15-2.18, P = 4.88 x 10~3). Additionally, compared to pregnant women who were in non-exposure group, 0-1 h/day exposure elevated the risk of LGA (OR = 1.69,95%CI = 1.22-2.33,P= 1.63 x 10~(-3)), while>l h/day exposure elevated the risk of small for gestational age, but were not significant (SGA, OR = 2.15,95% CI = 0.61-7.66, P = 024). In the stratification analysis, women aged 25-29 years and >30 years were predisposed to the influence of cooking oil fumes and have LGA newborns (OR = 1.73, 95% CI = 1.09-2.75, P = 0.02; OR = 1.72,95% CI = 1.07-2.77, P = 0.02, respectively). In conclusion, the present study suggests inverse U-shape dose response association between maternal exposure to cooking oil fumes during pregnancy and birth weight, and further studies are needed to verify the effect of cooking oil fumes on the birth weight.
机译：多年来研究了室内空气污染对新生儿出生体重的影响。在中国，食用油烟是​​室内空气污染的重要组成部分。但是，在中国，怀孕期间食用油烟是​​否会影响出生体重仍知之甚少。这项研究的目的是研究在中国新建立的准母婴队列中，孕妇食用油烟的暴露与出生体重之间的关系。我们最终纳入了2013年至2015年的1420名孕妇，并进行了为期一年的随访，直到后代出生。根据自我报告的暴露状态，我们将母亲分为非暴露组和暴露组，或三个暴露时间亚组，分别为0小时/天，0-1小时/天和> 1小时/天。通过使用多项式物流回归模型，我们发现怀孕的食用油烟暴露显着增加了大胎龄的风险（LGA，OR = 1.58,95％a = 1.15-2.18，P = 4.88 x 10〜3）。此外，与非暴露组孕妇相比，每天0-1小时暴露会增加LGA的风险（OR = 1.69,95％CI = 1.22-2.33，P = 1.63 x 10〜（-3）） ，但> lh /天的暴露会增加较小胎龄的风险，但并不显着（SGA，OR = 2.15,95％CI = 0.61-7.66，P = 024）。在分层分析中，年龄在25-29岁和> 30岁的女性易受食用油烟的影响，并有LGA新生儿（OR = 1.73，95％CI = 1.09-2.75，P = 0.02； OR = 1.72,95 ％CI ＝ 1.07-2.77，P ＝ 0.02）。总之，本研究表明孕妇孕期暴露于食用油烟与出生体重之间呈反U型剂量反应关系，还需要进一步的研究以验证食用油烟对出生体重的影响。

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  • 来源
    《The Science of the Total Environment》 |2018年第15期|822-830|共9页
  • 作者

    Lingling Wang; Weiyue Hu; Quanquan Guan; Guizhen Du; Ting Chen; Wei Wu; Yun Wang; Xinru Wang; Yankai Xia;

  • 作者单位

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    Nanjing Maternal and Child Health Medical Institute, Obstetrics and Gynecology Hospital Affiliated to Nanjing Medical University, Nanjing 210004, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    Suzhou Affiliated Hospital of Nanjing Medical University, 26 Daoqian Road, Suzhou 215002,JiangSu Province, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

    State Key Laboratory of Reproductive Medicine, Institute ofToxicology, Nanjing Medical University, Nanjing 211166, China,Key Laboratory of Modem Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, China;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Cooking oil fumes; Pregnancy exposure; Birth weight; Large for gestational age; Mother-child cohort;

    机译：食用油烟;怀孕暴露;出生体重;胎龄大;母婴队列;

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