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Design of 3D Active Multichannel Silicon Neural Microelectrode

机译:3D有源多通道硅神经微电极的设计

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摘要

To find a design method for 3D active multichannel silicon microelectrode, a microstructure of active neural recording system is presented, where two 2D probes, two integrated circuits and two spacers are microassembled on a 5 mm x 7 mm silicon platform, and 32 sites neural signals can be operated simultaneously. A theoretical model for measuring the neural signal by the silicon microelectrode is proposed based on the structure and fabrication process of a single-shank probe. The method of determining the dimensional parameters of the probe shank is discussed in the following three aspects, i. e. the structures of pallium and endocranium. coupled interconnecters noise, and strength characteristic of neural probe. The design criterion is to minimize the size of the neural probe as well as that the probe has enough stiffness to pierce the endocranium. The on-chip unity-gain bandpass amplifier has an overall gain of 42 dB over a bandwidth from 60 Hz to 10 kHz; and the DC-baseline stability circuit is of high input resistance above 30 MΩ to guarantee a cutoff frequency below 100 Hz. The circuit works in stimulating or recording modes. The conversion of the modes depends on the stimulating control signal.
机译:为了找到一种用于3D有源多通道硅微电极的设计方法,提出了一种有源神经记录系统的微观结构,其中在5 mm x 7 mm硅平台上微组装了两个2D探针,两个集成电路和两个垫片,并提供了32个位置的神经信号可以同时操作。基于单柄探针的结构和制造过程,提出了一种利用硅微电极测量神经信号的理论模型。在以下三个方面中讨论了确定探杆尺寸参数的方法。 e。钯和颅骨的结构。耦合互连器的噪声以及神经探针的强度特性。设计标准是最小化神经探针的尺寸,以及探针具有足够的刚度以刺穿颅骨。片上单位增益带通放大器在60 Hz至10 kHz的带宽内具有42 dB的总增益;直流基线稳定电路具有高于30MΩ的高输入电阻,以确保截止频率低于100 Hz。该电路以刺激或记录模式工作。模式的转换取决于激励控制信号。

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