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首页> 外文期刊>Proceedings of the Institution of Mechanical Engineers, Part H. Journal of Engineering in Medicine >Effects of bone density alterations on strain patterns in the pelvis: application of a finite element model
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Effects of bone density alterations on strain patterns in the pelvis: application of a finite element model

机译：骨密度改变对骨盆应变模式的影响：有限元模型的应用

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摘要

Insufficiency fractures occur when physiological loads are applied to bone deficient in mechanical resistance. A better understanding of pelvic mechanics and the effect of bone density alterations could lead to improved diagnosis and treatment of insufficiency fractures. This study aimed to develop and validate a subject-specific three-dimensional (3D) finite element (FE) model of a pelvis, to analyse pelvic strains as a function of interior and cortical surface bone density, and to compare high strain regions with common insufficiency fracture sites. The FE model yielded strong agreement between experimental and model strains. By means of the response surface method, changes to cortical surface bone density using the FE model were found to have a 60 per cent greater influence compared with changes in interior bone density. A small interaction was also found to exist between surface and interior bone densities (< 3 per cent), and a non-linear effect of surface bone density on strain was observed. Areas with greater increases in average principal strains with reductions in density in the FE model corresponded to areas prone to insufficiency fracture. Owing to the influence of cortical surface bone density on strain, it may be considered a strong global (non-linear) indicator for insufficiency fracture risk.
机译：当将生理负荷施加于机械抵抗力不足的骨骼时，就会发生骨折不足。对骨盆力学和骨密度改变的影响有更好的了解可以改善对功能不全骨折的诊断和治疗。这项研究旨在开发和验证骨盆的受试者特定三维（3D）有限元（FE）模型，分析骨盆应变与内部和皮质表面骨密度的函数关系，并比较高应变区域与常见骨折部位不足。 FE模型在实验菌株和模型菌株之间产生了强烈的一致性。通过响应表面方法，发现使用FE模型对皮质表面骨密度的变化与内部骨密度的变化相比，具有60％的更大影响。还发现表面和内部骨密度之间存在小的相互作用（<3％），并且观察到表面骨密度对应变的非线性影响。在有限元模型中，平均主应变增大而密度减小的区域对应于易于断裂的区域。由于皮质表面骨密度对应变的影响，可以认为它是骨折不足风险的强有力的整体（非线性）指标。

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