...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Progress in brain research >Chronic multiunit recordings in behaving animals: advantages and limitations.
【24h】

Chronic multiunit recordings in behaving animals: advantages and limitations.

机译：行为动物的慢性多单位录音：优点和缺点。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

By simultaneous recording from neural responses at many different loci at the same time, we can understand the interaction between neurons, and thereby gain insight into the network properties of neural processing, instead of the functioning of individual neurons. Here we will discuss a method for recording in behaving animals that uses chronically implanted micro-electrodes that allow one to track neural responses over a long period of time. In a majority of cases, multiunit activity, which is the aggregate spiking activity of a number of neurons in the vicinity of an electrode tip, is recorded through these electrodes, and occasionally single neurons can be isolated. Here we compare the properties of multiunit responses to the responses of single neurons in the primary visual cortex. We also discuss the advantages and disadvantages of the multiunit signal as opposed to a signal of single neurons. We demonstrate that multiunit recording provides a reliable and useful technique in cases where the neurons at the electrodes have similar response properties. Multiunit recording is therefore especially valuable when task variables have an effect that is consistent across the population of neurons. In the primary visual cortex, this is the case for figure-ground segregation and visual attention. Multiunit recording also has clear advantages for cross-correlation analysis. We show that the cross-correlation function between multiunit signals gives a reliable estimate of the average single-unit cross-correlation function. By the use of multiunit recording, it becomes much easier to detect relatively weak interactions between neurons at different cortical locations.
机译：通过同时记录来自许多不同基因座的神经反应，我们可以了解神经元之间的相互作用，从而深入了解神经处理的网络特性，而不是单个神经元的功能。在这里，我们将讨论一种使用长期植入的微电极在行为动物中进行记录的方法，该电极可以长时间跟踪神经反应。在大多数情况下，通过这些电极记录多单位活动，即电极尖端附近许多神经元的加标峰值活动，偶尔可以分离出单个神经元。在这里，我们比较了初级视觉皮层中多单位反应对单个神经元反应的特性。我们还将讨论与单个神经元信号相反的多单位信号的优缺点。我们证明，在电极神经元具有类似响应特性的情况下，多单元记录提供了可靠且有用的技术。因此，当任务变量具有在整个神经元群体中一致的效果时，多单元记录特别有价值。在主要的视觉皮层中，图形-地面隔离和视觉注意力就是这种情况。多单元记录对于互相关分析也具有明显的优势。我们表明，多单位信号之间的互相关函数给出了平均单单位互相关函数的可靠估计。通过使用多单元记录，检测不同皮质位置的神经元之间相对较弱的相互作用变得更加容易。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号