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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Effect of comorbid chronic diseases on prevalence and odds of depression in adults with diabetes.
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Effect of comorbid chronic diseases on prevalence and odds of depression in adults with diabetes.

机译：合并症慢性疾病对成年人糖尿病患病率和抑郁几率的影响。

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OBJECTIVE: The objective of this study was to determine the effect of coexisting chronic conditions on prevalence and odds of depression in individuals with diabetes. METHODS: Data on 1794 adults with diabetes from the 1999 National Health Interview Survey were analyzed. Six chronic conditions were identified: hypertension, coronary artery disease, chronic arthritis, stroke, chronic obstructive pulmonary disease, and end-stage renal disease. Chronic conditions were counted and categorized into 4 groups: diabetes alone, diabetes + 1 condition, diabetes + 2 conditions, and diabetes + 3 or more conditions. Prevalence of depression was calculated by number of chronic conditions and for each condition. Adjusted odds of depression were calculated by number of chronic conditions and for each chronic condition while simultaneously controlling for covariates and for each chronic condition using multiple logistic regression. STATA was used for statistical analyses. RESULTS: Using diabetes alone as reference, adjusted odds of major depression by number of conditions were: diabetes + 1 (1.31; 95% confidence interval [CI], 0.67-2.55), diabetes + 2 (2.09; 95% CI, 1.06-4.12), and diabetes + 3 or more (4.09; 95% CI, 2.04-8.17). Adjusted odds of major depression for each coexisting chronic conditions were: hypertension (1.22; 95% CI, 0.78-1.90), coronary artery disease (2.00; 95% CI, 1.27-3.14), chronic arthritis (2.02; 95% CI, 1.35-3.02), stroke (2.15; 95% CI, 1.10-4.31), chronic obstructive pulmonary disease (0.96; 95% CI, 0.52-1.81), and end-stage renal disease (1.19; 95% CI, 0.57-2.49). CONCLUSION: Odds of major depression are significantly increased among adults with diabetes in the presence of two or more coexisting chronic conditions, and coexistence of coronary artery disease, chronic arthritis, and stroke in particular, are associated with increased odds of major depression.
机译：目的：本研究的目的是确定慢性病共存对糖尿病患者患病率和抑郁几率的影响。方法：分析了1999年全国健康访问调查中1794名糖尿病患者的数据。确定了六种慢性疾病：高血压，冠状动脉疾病，慢性关节炎，中风，慢性阻塞性肺疾病和终末期肾脏疾病。计数慢性病并将其分为4组：单独的糖尿病，糖尿病+1种疾病，糖尿病+2种疾病和糖尿病+3种或更多疾病。抑郁症的患病率是通过慢性病的数量以及每种疾病的计算得出的。通过慢性病的数量和每种慢性病的数量计算调整后的抑郁几率，同时使用多元逻辑回归同时控制协变量和每种慢性病。 STATA用于统计分析。结果：仅以糖尿病为参考，按病情数量调整的重度抑郁的几率是：糖尿病+1（1.31; 95％置信区间[CI]，0.67-2.55），糖尿病+ 2（2.09; 95％CI，1.06- 4.12），以及糖尿病+ 3或更高（4.09; 95％CI，2.04-8.17）。对于每种并存的慢性病，​​调整后的严重抑郁的几率是：高血压（1.22; 95％CI，0.78-1.90），冠心病（2.00; 95％CI，1.27-3.14），慢性关节炎（2.02; 95％CI，1.35） -3.02），中风（2.15; 95％CI，1.10-4.31），慢性阻塞性肺疾病（0.96; 95％CI，0.52-1.81）和终末期肾脏疾病（1.19; 95％CI，0.57-2.49） 。结论：在患有两种或多种并存的慢性疾病的成年人中，成年人的严重抑郁的几率显着增加，尤其是冠状动脉疾病，慢性关节炎和中风的并存与严重抑郁的几率增加有关。

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