首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea.
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The effects of manipulating expectations through placebo and nocebo administration on gastric tachyarrhythmia and motion-induced nausea.

机译:通过服用安慰剂和Nocebo来操纵期望值对胃快速性心律失常和运动引起的恶心的作用。

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BACKGROUND: Interest in the role of expectation in the development of nausea and other adverse conditions has existed for decades. The purpose of this study was to examine the effects of manipulating expectations through the administration of placebos and nocebos on nausea and gastric tachyarrhythmia provoked by a rype.addElementToInclusions "Annotation", "Article" End If End If End Function 'doaddElements() ell sizes were too small for meaningful analysis, individuals in the PAN and BAN groups had numerically higher rates of use laxatives as the sole method of purging with respect to other ED groups. Excluding probands (those required to have used vomiting as a compensatory behavior) from the above analyses, 3.6% and 6.6% of participants with PBN and ANBN, respectively, used laxatives-up participants during drum rotation (p < .05). CONCLUSIONS: Inducing negative expectations through nocebo administration reduced nausea and gastric dysrhythmia during exposure to provocative motion, whereas positive placebos were ineffective for preventing symptom development. That manipulation of expectation affected gastric physiological responses as well as reports of symptoms, suggests an unspecified psychophysiological mechanism was responsible for the observed group differences. These results also suggest that patients preparing for difficult medical procedures may benefit most from being provided with detailed information about how unpleasant their condition may become.
机译:背景:人们对期望在恶心和其他不利条件发展中的作用的兴趣已有数十年了。这项研究的目的是研究通过服用安慰剂和nocebos对由rype.addElementToInclusions“ Annotation”,“ Article” End If End If End End End函数'doaddElements()ell大小引起的恶心和胃快速性心律失常的管理来操纵期望的影响太小而无法进行有意义的分析,PAN和BAN组中的个体使用泻药的数量在数值上更高,是其他ED组的唯一清除方法。从上述分析中除去先证者(需要使用呕吐作为补偿行为的先证者),分别有3.6%和6.6%的PBN和ANBN参与者在鼓旋转期间使用了泻药性参与者(p <.05)。结论:通过服用Nocebo引起的负面期望减少了暴露于刺激性运动期间的恶心和胃节律失常,而阳性安慰剂则无法有效地预防症状的发展。对期望的操纵会影响胃部的生理反应以及症状的报告,这表明未指定的心理生理机制是导致观察到的组差异的原因。这些结果还表明,为困难的医疗程序做准备的患者可能会受益于有关其病情可能变得多么不愉快的详细信息。

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