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Anxiety and chronic obstructive pulmonary disease: prevalence, impact, and treatment.

机译:焦虑症和慢性阻塞性肺疾病:患病率,影响和治疗。

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OBJECTIVE: This article reviews the prevalence of anxiety disorders in patients with chronic obstructive pulmonary disease (COPD) as well as the impact of comorbid anxiety on quality of life in patients with COPD. Published studies on three types of treatments for anxiety are then reviewed: psychopharmacology, psychotherapy, and pulmonary rehabilitation programs. MATERIALS AND METHODS: A PubMed search was conducted of the literature from 1966 through 2002 using the keywords anxiety, chronic obstructive pulmonary disease, respiratory diseases, obstructive lung diseases, and pulmonary rehabilitation. Any articles that discussed the prevalence of anxiety symptoms or anxiety disorders among patients with COPD, the impact of anxiety on patients with COPD, or the treatment of anxiety in COPD patients were included in this review. RESULTS: Anxiety disorders, especially generalized anxiety disorder (GAD) and panic disorder, occur at a higher rate in patients with COPD compared with the general population. Not surprisingly, anxiety has a significant and negative impact on quality of life of COPD patients. Nonetheless, few studies have examined pharmacological, psychotherapeutic, or pulmonary rehabilitation treatments for anxiety disorders in the context of COPD. Trials of nortriptyline, buspirone, and sertraline have been found to reduce symptoms of anxiety. Similarly, cognitive-behavioral programs that focus on relaxation and changes in thinking also produced declines in anxious symptoms. Finally, multicomponent pulmonary rehabilitation programs can also result in reductions in anxious symptoms. CONCLUSIONS: Studies examining the treatment of anxiety disorders in patients with COPD are promising, yet their efficacy needs to be established. The long-term effects of treatment of anxiety disorders on quality of life of COPD patients have yet to be explored.
机译:目的:本文回顾了慢性阻塞性肺疾病(COPD)患者的焦虑症患病率,以及合并症对COPD患者生活质量的影响。然后回顾了关于焦虑症的三种治疗方法的已发表研究:心理药理学,心理治疗和肺康复计划。材料与方法:使用关键词焦虑,慢性阻塞性肺疾病,呼吸系统疾病,阻塞性肺疾病和肺康复,对1966年至2002年的文献进行PubMed搜索。任何讨论COPD患者焦虑症状或焦虑症患病率,焦虑对COPD患者的影响或COPD患者焦虑症治疗的文章均纳入本评价。结果:与普通人群相比,COPD患者的焦虑症,尤其是广泛性焦虑症(GAD)和恐慌症的发生率更高。毫不奇怪,焦虑对COPD患者的生活质量有重大而负面的影响。尽管如此,很少有研究针对COPD背景下焦虑症的药理,心理治疗或肺部康复治疗进行研究。已经发现去甲替林,丁螺环酮和舍曲林的试验可减轻焦虑症状。同样,专注于放松和思维变化的认知行为程序也会导致焦虑症状的减轻。最后,多组分肺康复计划还可以减轻焦虑症状。结论:研究检查COPD患者焦虑症的治疗方法是有希望的,但尚需确定其疗效。焦虑症治疗对COPD患者生活质量的长期影响尚待探索。

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