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Prognosis of chronic fatigue in a community-based sample.

机译:基于社区的样本中慢性疲劳的预后。

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OBJECTIVE: This study examined predictors of fatigue severity and predictors of continued chronic fatigue status at wave 2 follow-up within a random, community-based sample of individuals previously evaluated in a wave 1 prevalence study of chronic fatigue and chronic fatigue syndrome that originally took place between 1995 and 1997. METHODS: Wave 1 data were from a larger community-based prevalence study of chronic fatigue syndrome. In the present study, a second wave of data were collected by randomly selecting a sample of participants from the wave 1 sample of 18,675 adults and readministering a telephone screening questionnaire designed to assess symptoms of chronic fatigue syndrome. RESULTS: Findings revealed that wave 1 fatigue severity was a predictor of fatigue severity at wave 2 in the overall sample of individuals with and without chronic fatigue. In the smaller sample of individuals with chronic fatigue, wave 1 fatigue severity, worsening of fatigue with physical exertion, and feeling worse for 24 hours or more after exercise significantly predicted continued chronic fatigue status (vs. improvement) at wave 2 follow-up. CONCLUSIONS: These findings underscore the prognostic validity of postexertional malaise in predicting long-term chronic fatigue and also highlight the importance of using population-based, representative random samples when attempting to identify long-term predictors of chronic fatigue at follow-up.
机译:目的:本研究检查了随机,以社区为基础的个体样本中第二次随访时疲劳严重程度的预测因素和持续慢性疲劳状态的预测因素,这些样本先前在慢性疲劳和慢性疲劳综合症的第一阶段流行性研究中得到了评估,该研究最初是采用方法:1995年至1997年之间。方法:第一波数据来自一项基于社区的较大规模的慢性疲劳综合征患病率研究。在本研究中,通过从18675名成年人的第一波样本中随机选择参与者样本并重新设计旨在评估慢性疲劳综合症症状的电话筛查问卷来收集第二波数据。结果:研究发现,在有和没有慢性疲劳的个体样本中,第1浪疲劳严重程度是第2浪疲劳严重程度的预测指标。在较小的具有慢性疲劳的个体样本中,第1浪疲劳严重度,因体育锻炼而使疲劳恶化以及运动后24小时或更长时间感到不适的情况,显着预测了第2浪随访时持续的慢性疲劳状态(相对于改善)。结论:这些发现强调了劳累后不适在预测长期慢性疲劳中的预后有效性,也突出了在尝试确定随访中慢性疲劳的长期预测因素时,使用以人群为基础的代表性随机样本的重要性。

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