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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Lower mortality among stroke patients with schizophrenia: a nationwide population-based study.
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Lower mortality among stroke patients with schizophrenia: a nationwide population-based study.

机译：在患有精神分裂症的中风患者中降低死亡率：一项基于人群的全国性研究。

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OBJECTIVE: To examine 90-day mortality among schizophrenia patients who suffered a recent stroke, using population-based data and a retrospective cohort design. Increasing evidence demonstrates a higher cardiovascular risk for schizophrenia patients compared with the general population. There are no data on stroke outcomes among schizophrenia patients. METHODS: Data were derived from the Taiwan National Health Insurance Research Database and Cause of Death Data File in Taiwan. During 2002 to 2004, 485 schizophrenia patients hospitalized for stroke were identified. We randomly selected 2,425 stroke patients without schizophrenia who were matched to the study group on sex, age, intensive care unit admission, length of stay, and stroke type. Stratified Cox proportional hazard regressions stratified by age, sex, intensive care unit admission, length of stay, and stroke type were performed to compute the 90-day survival rate, after adjusting for demographic variables and selected medical comorbidities. RESULTS: Among the 2,910 sampled patients, 258 patients (8.9%) died within 90 days of their index hospitalization, 18 (3.7%) from the study group and 240 (9.9%) from the comparison group (p < .001). After adjusting for demographic and comorbidity factors, stratified Cox proportional hazard regressions confirmed likewise showed that 90-day mortality was less likely among stroke patients with schizophrenia relative to stroke patients without schizophrenia (hazard ratio, 0.35; 95% confidence interval, 0.21-0.57; p < .001). CONCLUSION: A 90-day mortality among acute stroke patients with schizophrenia is significantly lower than that of stroke patients without schizophrenia.
机译：目的：使用基于人群的数据和回顾性队列设计，调查最近中风的精神分裂症患者的90天死亡率。越来越多的证据表明，与普通人群相比，精神分裂症患者的心血管风险更高。没有关于精神分裂症患者中风预后的数据。方法：数据来自台湾国家健康保险研究数据库和台湾死亡原因数据文件。在2002年至2004年期间，确定了485例因中风住院的精神分裂症患者。我们从性别，年龄，重症监护病房，住院时间和中风类型方面随机选择了2,425名无精神分裂症的中风患者，与研究组相匹配。在调整了人口统计学变量和所选的合并症之后，按年龄，性别，重症监护病房，住院时间和中风类型分层进行分层Cox比例风险回归，以计算90天生存率。结果：在2,910名样本患者中，有258名患者（8.9％）在其指数住院后90天内死亡，研究组18例（3.7％），比较组240例（9.9％）（p <.001）。在调整了人口统计学因素和合并症因素后，分层的Cox比例风险回归分析同样表明，与没有精神分裂症的中风患者相比，患有精神分裂症的中风患者的90天死亡率可能性更低（危险比，0.35; 95％置信区间，0.21-0.57; p <.001）。结论：患有精神分裂症的急性中风患者的90天死亡率显着低于没有精神分裂症的中风患者。

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