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PHARMACOKINETICS & NEUROPHYSIOLOGY

机译:药代动力学与神经生理学

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摘要

Medications administered in clinical practice obtain their herapeutic effect only to the extent that the drug is present in the appropriate concentration at the desired site. To achieve this goal,the prescribing clinician must be aware of how a drug may interact with the physiology of the patient. Pharmacokinetics is the study of this process with a focus on the absorption, distribution,metabolism, and excretion of the drug. This article reviews these four processes with a discussion of the effects of route of administration. Emphasis is given to the differences between pediatric and adult populations.
机译:在临床实践中施用的药物仅在药物以所需浓度以适当浓度存在于所需部位的情况下才能获得其治疗作用。为了实现这一目标,开处方的临床医生必须知道药物如何与患者的生理相互作用。药代动力学是对这一过程的研究,重点是药物的吸收,分布,代谢和排泄。本文通过讨论管理路径的效果来回顾这四个过程。着重强调了小儿和成年人口之间的差异。

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