首页> 外文期刊>Psychosomatics >Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanism.
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Comorbid somatic symptoms and functional status in patients with fibromyalgia and chronic fatigue syndrome: sensory amplification as a common mechanism.

机译:纤维肌痛和慢性疲劳综合征患者的躯体症状合并症和功能状态:感觉放大是一种常见机制。

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摘要

BACKGROUND: Somatic symptoms are common in conditions such as fibromyalgia (FM) and chronic fatigue syndrome (CFS). OBJECTIVE: Authors investigated a potential shared pathologic mechanism: a generalized perceptual abnormality where there is heightened responsiveness to varied sensory stimulation, including pain. METHOD: A composite measure of sensory sensitivity was created and compared with measures of somatic symptoms, comorbid psychological disturbances, and self-reported physical functioning in 38 patients with FM and/or CFS. RESULTS: Sensory amplification influenced physical functioning indirectly through pain intensity, and physical symptoms and fatigue also independently contributed to physical functioning. CONCLUSION: Sensory amplification may be an underlying pathophysiologic mechanism in these disorders that is relatively independent of depression and depressive symptoms.
机译:背景:躯体症状在诸如纤维肌痛(FM)和慢性疲劳综合征(CFS)等疾病中很常见。目的:作者研究了一种潜在的共有病理机制:一种普遍的知觉异常,对各种感觉刺激(包括疼痛)的反应性增强。方法:创建了一种感官敏感性的综合量度,并与38例FM和/或CFS患者的躯体症状,合并症,心理障碍以及自我报告的身体功能进行了比较。结果:感觉增强通过疼痛强度间接影响身体机能,身体症状和疲劳也独立地促进身体机能。结论:感觉增强可能是这些疾病的潜在病理生理机制,与抑郁和抑郁症状相对独立。

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