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Far-Wall Pseudoenhancement During Contrast-Enhanced Ultrasound of the Carotid Arteries: Clinical Description and In Vitro Reproduction

机译:颈动脉超声造影中的远距离伪增强:临床描述和体外繁殖

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摘要

The present study describes the presence of pseudoenhancement during contrast-enhanced ultrasound (CEUS) imaging of human carotid arteries and the reproduction of this pseudoenhancement in vitro. Seventy patients underwent bilateral CEUS examination of the carotid arteries using a Philips iU22 ultrasound system equipped with a L9-3 ultrasound probe and SonoVue microbubble contrast. During CEUS of the carotid arteries, we identified enhancement in close proximity to the far wall, parallel to the main lumen. The location of this enhancement does not correlate to the anatomical location of a parallel vessel. To corroborate the hypothesis that this is a pseudoenhancement artifact, the enhancement was recreated in a tissue-mimicking material phantom, using the same ultrasound system, settings and contrast agent as the patient study. The phantom study showed that pseudoenhancement may be present during vascular CEUS and that the degree of pseudoenhancement is influenced by the size and concentration of the microbubbles. During vascular CEUS, identification of the artifact is important to prevent misinterpretation of enhancement in and near the far wall.
机译:本研究描述了人类颈动脉造影增强超声(CEUS)成像过程中伪增强的存在以及这种伪增强在体外的繁殖。使用装有L9-3超声探头和SonoVue微泡造影剂的Philips iU22超声系统,对70位患者的颈动脉进行了双侧CEUS检查。在颈动脉CEUS期间,我们发现与远端壁平行且与主腔平行的区域增强。这种增强的位置与平行血管的解剖位置不相关。为了证实这是伪增强伪像的假设,使用与患者研究相同的超声系统,设置和造影剂,在模仿组织的材料模型中重新创建了增强效果。幻像研究表明,在血管性CEUS期间可能会出现假性增强,并且假性增强的程度受微气泡的大小和浓度影响。在血管性CEUS期间,对伪影的识别对于防止对远端壁及其附近增强的误解很重要。

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