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首页> 外文期刊>Ultrasound in Medicine and Biology >Second harmonic and subharmonic for non-linear wideband contrast imaging using a capacitive micromachined ultrasonic transducer array
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Second harmonic and subharmonic for non-linear wideband contrast imaging using a capacitive micromachined ultrasonic transducer array

机译：使用电容微加工超声换能器阵列进行非线性宽带对比成像的二次谐波和次谐波

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摘要

When insonified with suitable ultrasound excitation, contrast microbubbles generate various non-linear scattered components, such as the second harmonic (2H) and the subharmonic (SH). In this study, we exploit the wide frequency bandwidth of capacitive micromachined ultrasonic transducers (CMUTs) to enhance the response from ultrasound contrast agents by selective imaging of both the 2H and SH components simultaneously. To this end, contrast images using the pulse inversion method were recorded with a 64-element CMUT linear array connected to an open scanner. In comparison to imaging at 2H alone, the wideband imaging including both the 2H and SH contributions provided up to 130% and 180% increases in the signal-to-noise and contrast-to-tissue ratios, respectively. The wide-frequency band of CMUTs offers new opportunities for improved ultrasound contrast agent imaging.
机译：当用适当的超声激发声波照射时，对比微气泡会产生各种非线性的散射成分，例如二次谐波（2H）和次谐波（SH）。在这项研究中，我们利用电容微机械超声换能器（CMUT）的宽频带宽，通过同时对2H和SH分量进行选择性成像来增强超声造影剂的响应。为此，使用连接到开放式扫描仪的64元素CMUT线性阵列记录了使用脉冲反转方法的对比图像。与仅在2H下成像相比，包括2H和SH贡献的宽带成像分别将信噪比和对比组织比率提高了130％和180％。 CMUT的宽频带为改进超声造影剂成像提供了新的机会。

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