Fetal hamartoma constitutes a rare benign lesion of the mesenchymal tissue. We describe here the antenatal diagnosis and management of a giant hepatic mesenchymal hamartoma in conjunction with placental mesenchymal dysplasia. A 29-year-old woman, gravida 2 para 1, was referred to our tertiary center at 13 + 3 weeks'gestation because of a large space-occupying lesion arising from a multiloc-ulated placenta. The initial sonographic findings were suspicious for a partial hydatidiform placenta in addition to a stalked hypoechogenic round structure connected to the placenta, consistent with a placental chorangioma. Maternalbeta-human chorionic gonadotropin (beta-hCG) and alpha fetoprotein (AFP) levels were within normal ranges. The fetus showed normal biometric measurements. Nuchal translucency screening revealed a risk of 1 in 2959 for trisomy 21. Biweekly follow-up scans were performed. At 20 weeks, targeted ultrasound revealed a hypoechogenic infradiaphragmatic cystic mass (Figure 1). The lesion measured 19 x 17x 19 mm and showed marked septation and rapid growth, reaching a size of 74 x 47 x 50 mm by 23 weeks without measurable perfusion (Figure 2). At this time the diagnosis of a large progredient hamartoma was assumed. At 27 + 4 weeks inpatient admission was necessary because of preterm labor, prompting an immediate Cesarean section. Preoperative ultrasound showed continuing growth of the hepatic mass to 98 x 73 x 86 mm. A premature female infant was delivered weighing 1452 g, with Apgar scores of 5 and 8 at 5 and 10 min, respectively. The infant was immediately admitted to the neonatal unit in good general condition.
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机译：胎儿错构瘤是间质组织的一种罕见的良性病变。我们在这里描述一个巨大的肝间充质错构瘤与胎盘间质不典型增生的产前诊断和管理。一名孕妇在妊娠13 + 3周时被引到我们的三级中心，是一名孕妇，妊娠2第1段，这是由于多部位胎盘引起的占位大的病变。最初的超声检查结果可疑为部分葡萄胎状胎盘，此外还有与胎盘相连的低回声的圆形结构，与胎盘胆管瘤一致。孕妇β-绒毛膜促性腺激素（β-hCG）和甲胎蛋白（AFP）水平在正常范围内。胎儿显示出正常的生物测量结果。颈部半透明性筛查显示2959年三体性疾病的风险为1。21进行了双周随访扫描。在20周时，定向超声检查显示出低回声下dia肌囊性肿块（图1）。病变尺寸为19 x 17x 19 mm，表现出明显的分隔并迅速生长，到23周时大小达到74 x 47 x 50 mm，而没有可测量的灌注（图2）。此时，假定诊断为大型多发性错构瘤。由于早产，必须在27 + 4周住院，促使立即剖腹产。术前超声显示肝脏肿块持续增长至98 x 73 x 86 mm。分娩的早产女婴重1452克，在5分钟和10分钟时Apgar评分分别为5和8。婴儿被立即送入新生儿，状况良好。
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