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首页> 外文期刊>Urology >Impact of Parkinson's disease on continence after radical prostatectomy.
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Impact of Parkinson's disease on continence after radical prostatectomy.

机译：根治性前列腺切除术后帕金森氏病对尿失禁的影响。

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OBJECTIVES: It is widely believed that men with idiopathic Parkinson's disease (PD) should not undergo prostate surgery because of the prohibitively high risk of incontinence. However, the data supporting this conclusion were based on cohorts undergoing prostate surgery for voiding dysfunction, not for cancer control. Because both prostate cancer and PD are predominantly diseases of the elderly, it is likely that some men are concurrently diagnosed with both disorders who would otherwise be good candidates for radical prostatectomy (RP). However, the urinary outcomes in men with PD undergoing RP are unknown. Thus, it is possible that men with PD have been denied a potentially curative surgery only on the basis of long-standing assumptions. We addressed this issue by examining a cohort of men with PD who underwent RP at our institution. METHODS: We retrospectively reviewed a cohort of men who had undergone RP at our institution from 1990 to 2000. These men were surveyed 1 year after their surgery to determine their continence status, and their records were reviewed to determine whether any men had been preoperatively diagnosed with PD. RESULTS: Of the 8415 men undergoing RP during the study period, 20 had PD and were included in our study. Their de novo incontinence rate at 1 year was 24%, with no patient requiring more than one to two pads per day. CONCLUSIONS: Most men with PD undergoing RP remained continent 1 year after surgery. Additional studies with longer follow-up are required to determine whether this remains true over time.
机译：目的：普遍认为，患有特发性帕金森氏病（PD）的男性不应进行前列腺手术，因为其失禁的风险极高。但是，支持该结论的数据是基于进行前列腺手术的患者排尿障碍，而不是为了控制癌症。由于前列腺癌和PD都是老年人的主要疾病，因此有可能同时诊断出一些男性患有这两种疾病，否则它们将是进行前列腺癌根治术（RP）的理想人选。但是，PD进行RP的PD患者的泌尿结局尚不清楚。因此，仅基于长期的假设，PD男性有可能被拒绝进行治愈性手术。我们通过检查一组在我们机构接受过RP治疗的PD男性患者来解决此问题。方法：我们回顾性研究了1990年至2000年在我们机构接受过RP手术治疗的一组男性。这些男性患者在手术后1年接受了调查，以确定其节制状态，并对其记录进行了检查以确定是否有任何男性被术前诊断过。与PD。结果：在研究期间的8415例接受RP的男性中，有20例患有PD，被纳入我们的研究。他们在一年中从头失禁的比例为24％，没有患者每天需要超过一到两个衬垫。结论：PD手术后PD的大多数男性在手术后1年仍留在大陆。需要进行更多的随访研究，以确定随着时间的推移，这种情况是否仍然成立。

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