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Results of unilateral genitofemoral nerve grafts with contralateral nerve sparing during radical prostatectomy.

机译:前列腺癌根治术中单侧生殖股神经移植对侧神经保留的结果。

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OBJECTIVES: To evaluate the success of erectile function preservation and recovery in a select group of patients with extensive disease unilaterally on biopsy who were candidates for unilateral nerve sparing and contralateral genitofemoral interposition nerve-grafting radical prostatectomy (RP). Because of its low donor site morbidity, the genitofemoral nerve is an appealing donor source for cavernous nerve grafting during RP. Although evidence has shown that sural interposition nerve grafts during RP preserve erectile function, the evidence for genitofemoral nerve grafts is limited. METHODS: Nerve-sparing RP was performed according to the technique of Walsh on 22 patients with prostate cancer. At follow-up, the patients completed an 11-item self-report questionnaire that included the erectile function (EF) domain of the International Index of Erectile Function. RESULTS: The mean patient age was 62 years (range 48 to 76). The mean follow-up time was 23 months (range 9 to 37). Of the 22 patients, 3 reported no erectile dysfunction (ED) (EF score 26 to 30), 3 reported mild ED (EF score 22 to 25), 1 reported moderate ED (EF score 11 to 16), and 15 reported severe ED (EF score less than 11). Eight men continued to experience mild chronic thigh or scrotal numbness after the genitofemoral nerve graft procedure. CONCLUSIONS: The benefits of unilateral nerve grafting with the genitofemoral nerve remain uncertain. A prospective randomized trial is warranted before the widespread adoption of unilateral nerve grafting.
机译:目的:评估部分活检中单侧广泛保留单侧神经保留和对侧股间插入神经移植根治性前列腺切除术(RP)的广泛疾病患者的勃起功能保留和恢复的成功性。由于供体部位的发病率低,生殖器股神经是RP期间海绵状神经移植的诱人供体来源。尽管有证据表明在RP期间腓肠肌间神经移植保留了勃起功能,但生殖股神经移植的证据有限。方法:采用Walsh技术对22例前列腺癌患者进行保留神经的RP。随访时,患者完成了一项11项自我报告调查表,其中包括国际勃起功能指数中的勃起功能(EF)域。结果:平均患者年龄为62岁(范围48至76)。平均随访时间为23个月(范围9至37)。在这22例患者中,有3例未报告勃起功能障碍(ED)(EF评分为26至30),3例报告为轻度ED(EF评分为22至25),1例为中度ED(EF评分为11至16),15例为严重ED (EF分数小于11)。八名男性生殖器股神经移植术后继续出现轻度的慢性大腿或阴囊麻木。结论:em股神经移植单侧神经的益处尚不确定。在广泛采用单侧神经移植之前,有必要进行一项前瞻性随机试验。

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