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首页> 外文期刊>Talanta: The International Journal of Pure and Applied Analytical Chemistry >Ultrasonic assisted synthesis of adenosine triphosphate capped manganese-doped ZnS quantum dots for selective room temperature phosphorescence detection of arginine and methylated arginine in urine based on supramolecular Mg ~2-adenosine triphosphate-arginine ternary system
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Ultrasonic assisted synthesis of adenosine triphosphate capped manganese-doped ZnS quantum dots for selective room temperature phosphorescence detection of arginine and methylated arginine in urine based on supramolecular Mg ~2-adenosine triphosphate-arginine ternary system

机译:基于超分子Mg〜2-腺苷三磷酸-精氨酸三元体系的超声辅助合成三磷酸腺苷包覆的锰掺杂ZnS量子点,用于选择性室温磷光检测尿液中的精氨酸和甲基化精氨酸

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摘要

An ultrasonic assisted approach was developed for rapid synthesis of highly water soluble phosphorescent adenosine triphosphate (ATP)-capped Mn-doped ZnS QDs. The prepared ATP-capped Mn-doped ZnS QDs allow selective phosphorescent detection of arginine and methylated arginine based on the specific recognition nature of supramolecular Mg ~2-ATP-arginine ternary system in combination with the phosphorescence property of Mn-doped ZnS QDs. The developed QD based probe gives excellent selectivity and reproducibility (1.7% relative standard deviation for 11 replicate detections of 10 μM arginine) and low detection limit (3 s, 0.23 μM), and favors biological applications due to the effective elimination of interference from scattering light and autofluorescence.
机译:开发了一种超声辅助方法,用于快速合成高度水溶性的磷光三磷酸腺苷(ATP)包覆的Mn掺杂的ZnS QD。基于超分子Mg〜2-ATP-精氨酸三元系统的特异性识别性质以及Mn掺杂的ZnS QDs的磷光特性,制备的ATP封端的Mn掺杂的ZnS QDs可以选择性地检测精氨酸和甲基化的精氨酸。研发的基于QD的探针具有出色的选择性和重现性(对于10μM精氨酸的11次重复检测,相对标准偏差为1.7%)和低检测限(3 s,0.23μM),由于有效消除了来自散射的干扰,因此有利于生物学应用光和自发荧光。

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