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首页> 外文期刊>The American Journal of Surgery >Colon preparation and surgical site infection.
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Colon preparation and surgical site infection.

机译：结肠准备和手术部位感染。

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BACKGROUND: Colon preparation for elective colon resection to reduce surgical site infection (SSI) remains controversial. METHODS: A review of the published literature was undertaken to define evidence-based practices for colon preparation for elective colon resection. RESULTS: Seventy years of surgical literature has documented that mechanical bowel preparation alone does not reduce SSI. A body of clinical trials has documented the benefits of oral antibiotic bowel preparation compared with a placebo in the reduction of SSI. Clinical trials show the addition of the oral antibiotic bowel preparation to appropriate systemic preoperative preventive antibiotics provide the lowest rates of SSI. CONCLUSIONS: Mechanical bowel preparation alone does not reduce rates of SSI, but oral antibiotic preparation and systemic preoperative antibiotics are superior when compared with systemic antibiotics alone. Additional clinical trials are necessary to define the best combined overall mechanical and oral antibiotic regimen for elective colon surgery.
机译：背景：为减少手术部位感染（SSI）而进行的选择性结肠切除术的结肠准备仍存在争议。方法：对发表的文献进行回顾，以定义基于证据的结肠准备术，以进行选择性结肠切除。结果：七十年的外科手术文献证明，仅机械准备肠并不能降低SSI。大量的临床试验证明，口服抗生素清肠制剂与安慰剂相比可减少SSI。临床试验表明，在适当的全身术前预防性抗生素中添加口服抗生素肠道制剂可提供最低的SSI发生率。结论：单独使用机械性肠道准备并不能降低SSI发生率，但与单独使用全身性抗生素相比，口服抗生素制剂和全身性术前抗生素是更好的选择。为确定择期结肠手术的最佳综合机械和口服抗生素治疗方案，还需要进行其他临床试验。

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