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首页> 外文期刊>The American Journal of Tropical Medicine and Hygiene >A systematic review of the literature on cystic echinococcosis frequency worldwide and its associated clinical manifestations
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A systematic review of the literature on cystic echinococcosis frequency worldwide and its associated clinical manifestations

机译:关于全世界囊性棘球cc病频率及其相关临床表现的文献的系统综述

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摘要

A systematic literature review of cystic echinoccocosis (CE) frequency and symptoms was conducted. Studies without denominators, original data, or using one serological test were excluded. Random-effect log-binomial models were run for CE frequency and proportion of reported symptoms where appropriate. A total of 45 and 25 articles on CE frequency and symptoms met all inclusion criteria. Prevalence of CE ranged from 1% to 7% in community-based studies and incidence rates ranged from 0 to 32 cases per 100,000 in hospital-based studies. The CE prevalence was higher in females (Prevalence Proportion Ratio: 1.35 [95% Bayesian Credible Interval: 1.16-1.53]) and increased with age. The most common manifestations of hepatic and pulmonary CE were abdominal pain (57.3% [95% confidence interval [CI]: 37.3-76.1%]) and cough (51.3% [95% CI: 35.7-66.7%]), respectively. The results are limited by the small number of unbiased studies. Nonetheless, the age/gender prevalence differences could be used to inform future models of CE burden.
机译:进行了系统的文献回顾性囊性棘球oc病(CE)的频率和症状。排除没有分母,原始数据或仅使用一项血清学检查的研究。在适当的情况下,针对CE频率和所报告症状的比例运行随机效应对数二项式模型。共有45篇和25篇关于CE频率和症状的文章符合所有纳入标准。在社区研究中,CE的患病率从1%到7%不等,在医院研究中,每10万人中CE的发生率在0到32例之间。女性的CE患病率较高(患病率:1.35 [95%贝叶斯可信区间:1.16-1.53​​]),并且随着年龄的增长而增加。肝和肺CE的最常见表现分别是腹痛(57.3%[95%置信区间[CI]:37.3-76.1%])和咳嗽(51.3%[95%CI:35.7-66.7%])。结果受到少数无偏研究的限制。尽管如此,年龄/性别患病率的差异可以用来为将来的CE负担模型提供依据。

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